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Study · Animal study (in vivo) · rat · 2017

2 results

Duodenal-jejunal bypass changes the composition of the gut microbiota.

Kashihara H, Shimada M, Yoshikawa K, Higashijima J, Nakao T, Nishi M, Takasu C

Surgery today13 Jul 2016Cited by 7 (Europe PMC)

PMID27412617 (opens in a new tab)DOI10.1007/s00595-016-1373-x (opens in a new tab)PepBankPUB-27412617
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Other

    In OLETF rats, the liraglutide group had numerically higher Bacteroidia (33.2 %/14.1 %) than the sham group (10.8 %/11.6 %); no statistical test is reported.

    In plain wordsIn rats, the liraglutide group had numerically more Bacteroidia gut bacteria than the sham group; no statistical test is reported.

    Peptide
    Liraglutide
    Outcome
    IncreaseBacteroidia abundance in gut microbiota
    Study

    ratn: not reported in source

    OLETF rat
    Comparator
    Sham operation
    Outcome group
    Gut microbiota · Gastrointestinal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The DJB group showed a decrease in Bacteroidia in comparison to the other two groups (DJB, 3.9 %/2.8 %; sham, 10.8 %/11.6 %; liraglutide, 33.2 %/14.1 %).
    2 context sentences
    Summary · context
    Six male 16-week-old OLETF rats were divided into three groups: a DJB group, a sham operation group, and a daily injection with a GLP-1 receptor agonist (liraglutide) group.
    Summary · context
    The gut microbiota of the three groups was analyzed at postoperative week 8 using the PCR-clone library method targeting the 16S ribosomal RNA gene.
  2. 02AnimalAnimal study (in vivo)Other

    In OLETF rats, the liraglutide group had numerically lower Gammaproteobacteria (0 %/0.1 %) than the sham group (0.2 %/1.2 %); no statistical test is reported.

    In plain wordsIn rats, the liraglutide group had numerically fewer Gammaproteobacteria gut bacteria than the sham group; no statistical test is reported.

    Peptide
    Liraglutide
    Outcome
    DecreaseGammaproteobacteria abundance in gut microbiota
    Study

    ratn: not reported in source

    OLETF rat
    Comparator
    Sham operation
    Outcome group
    Gut microbiota · Gastrointestinal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In addition, DJB markedly increased the ratio of Gammaproteobacteria (DJB, 10.8 %/13.7 %; sham, 0.2 %/1.2 %; liraglutide, 0 %/0.1 %).
    2 context sentences
    Summary · context
    Six male 16-week-old OLETF rats were divided into three groups: a DJB group, a sham operation group, and a daily injection with a GLP-1 receptor agonist (liraglutide) group.
    Summary · context
    The gut microbiota of the three groups was analyzed at postoperative week 8 using the PCR-clone library method targeting the 16S ribosomal RNA gene.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:10 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:05 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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