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Study · Animal study (in vivo) · catla catla (fish) · 2016

12 results

Molecular characterization of kisspeptin gene and effect of nano-encapsulted kisspeptin-10 on reproductive maturation in Catla catla.

Rather MA, Bhat IA, Gireesh-Babu P, Chaudhari A, Sundaray JK, Sharma R

Domestic animal endocrinology3 Mar 2016Cited by 33 (Europe PMC)

PMID27088601 (opens in a new tab)DOI10.1016/j.domaniend.2016.01.005 (opens in a new tab)PepBankPUB-27088601
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study12

7 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In Catla catla, GnRH mRNA expression in fish injected with K-10 declined after 6 h.

    In plain wordsIn the fish Catla catla, injected kisspeptin‑10 was followed by a fall in GnRH gene activity after 6 hours.

    Peptide
    Kisspeptin-10
    Outcome
    DecreaseGnRH mRNA expression after K-10
    Study

    Catla catla (fish)n: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · injectionAs given in this study (Catla catla (fish)).

    Source sentences

    Summary
    The mRNA expression of reproductive genes (GnRH, LH, and FSH) in fish injected with K-10 declined after 6 h, whereas those injected with CK-10 showed controlled and a sustained surge of mRNA expression of these genes with a peak at 12 h.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In Catla catla, LH mRNA expression in fish injected with K-10 declined after 6 h.

    In plain wordsIn the fish Catla catla, injected kisspeptin‑10 was followed by a fall in LH gene activity after 6 hours.

    Peptide
    Kisspeptin-10
    Outcome
    DecreaseLH mRNA expression after K-10
    Study

    Catla catla (fish)n: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · injectionAs given in this study (Catla catla (fish)).

    Source sentences

    Summary
    The mRNA expression of reproductive genes (GnRH, LH, and FSH) in fish injected with K-10 declined after 6 h, whereas those injected with CK-10 showed controlled and a sustained surge of mRNA expression of these genes with a peak at 12 h.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In Catla catla, FSH mRNA expression in fish injected with K-10 declined after 6 h.

    In plain wordsIn the fish Catla catla, injected kisspeptin‑10 was followed by a fall in FSH gene activity after 6 hours.

    Peptide
    Kisspeptin-10
    Outcome
    DecreaseFSH mRNA expression after K-10
    Study

    Catla catla (fish)n: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · injectionAs given in this study (Catla catla (fish)).

    Source sentences

    Summary
    The mRNA expression of reproductive genes (GnRH, LH, and FSH) in fish injected with K-10 declined after 6 h, whereas those injected with CK-10 showed controlled and a sustained surge of mRNA expression of these genes with a peak at 12 h.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In Catla catla, fish injected with chitosan-encapsulated K-10 (CK-10) showed a controlled and sustained surge of GnRH mRNA expression, peaking at 12 h.

    In plain wordsIn the fish Catla catla, packed kisspeptin‑10 gave a sustained rise in GnRH gene activity, peaking at 12 hours.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseGnRH mRNA expression after CK-10
    Study

    Catla catla (fish)n: not reported in source

    Comparator
    K-10
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · injectionAs given in this study (Catla catla (fish)).

    Source sentences

    Summary
    The mRNA expression of reproductive genes (GnRH, LH, and FSH) in fish injected with K-10 declined after 6 h, whereas those injected with CK-10 showed controlled and a sustained surge of mRNA expression of these genes with a peak at 12 h.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In Catla catla, fish injected with chitosan-encapsulated K-10 (CK-10) showed a controlled and sustained surge of LH mRNA expression, peaking at 12 h.

    In plain wordsIn the fish Catla catla, packed kisspeptin‑10 gave a sustained rise in LH gene activity, peaking at 12 hours.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseLH mRNA expression after CK-10
    Study

    Catla catla (fish)n: not reported in source

    Comparator
    K-10
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · injectionAs given in this study (Catla catla (fish)).

    Source sentences

    Summary
    The mRNA expression of reproductive genes (GnRH, LH, and FSH) in fish injected with K-10 declined after 6 h, whereas those injected with CK-10 showed controlled and a sustained surge of mRNA expression of these genes with a peak at 12 h.
  6. 06AnimalAnimal study (in vivo)Efficacy outcome

    In Catla catla, fish injected with chitosan-encapsulated K-10 (CK-10) showed a controlled and sustained surge of FSH mRNA expression, peaking at 12 h.

    In plain wordsIn the fish Catla catla, packed kisspeptin‑10 gave a sustained rise in FSH gene activity, peaking at 12 hours.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseFSH mRNA expression after CK-10
    Study

    Catla catla (fish)n: not reported in source

    Comparator
    K-10
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · injectionAs given in this study (Catla catla (fish)).

    Source sentences

    Summary
    The mRNA expression of reproductive genes (GnRH, LH, and FSH) in fish injected with K-10 declined after 6 h, whereas those injected with CK-10 showed controlled and a sustained surge of mRNA expression of these genes with a peak at 12 h.
  7. 07AnimalAnimal study (in vivo)Efficacy outcome

    In Catla catla, histologic examination of ovaries indicated a pronounced effect of CK-10 on maturation and gonadal development; the direction is not stated.

    In plain wordsIn the fish Catla catla, packed kisspeptin‑10 had a marked effect on ovary development on tissue examination.

    Peptide
    Kisspeptin-10
    Outcome
    Direction not reportedOvarian maturation and gonadal development after CK-10
    Study

    Catla catla (fish)n: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · injectionAs given in this study (Catla catla (fish)).

    Source sentences

    Summary
    Histologic examination of ovaries indicated a pronounced effect of CK-10 on maturation and gonadal development.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 08AnimalEndogenous levelAnimal study (in vivo)Other

    In Catla catla, kiss1 and kiss1rb mRNA were mainly expressed in the brain, pituitary gland and gonads.

    In plain wordsIn the fish Catla catla, the genes for the body's own kisspeptin and its receptor were mainly active in the brain, pituitary and gonads.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicablekiss1 and kiss1rb mRNA tissue distribution
    Study

    Catla catla (fish)n: not reported in source

    Catla catla basal tissues
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    The expression patterns of kiss1 and kiss1rb messenger RNA (mRNA) in basal tissues revealed that they are mainly expressed in the brain, pituitary gland, and gonads.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

Studies that did not test the peptide alone4

In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Kisspeptin-10.

  1. 09LabNot a test of Kisspeptin-10 aloneIn vitro (cell-free)Other

    The cloned kiss1 cDNA of Catla catla is 754 bp, with an open reading frame of 351 bp encoding a putative protein of 116 amino acids.

    In plain wordsResearchers cloned the kisspeptin gene of the fish Catla catla and described its length.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicablekiss1 cDNA and protein length
    Study

    n: not reported in source

    Cloned kiss1 gene
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Measurements

    kiss1 cDNA length
    754 bp
    Catla catla
    open reading frame
    351 bp
    kiss1
    putative protein length
    116 amino acids
    kiss1

    Source sentences

    Summary
    The full-length complementary DNA sequence of kiss1 is 754 bp with an open reading frame of 351 bp that encodes a putative protein of 116 amino acids.

    In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.

  2. 10LabNot a test of Kisspeptin-10 aloneIn vitro (cell-free)Other

    Chitosan-encapsulated K-10 (CK-10) nanoparticles had a particle size of 125 nm.

    In plain wordsIn lab tests, kisspeptin‑10 packed in chitosan nanoparticles gave particles 125 nm in size.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableCK-10 nanoparticle size
    Study

    n: not reported in source

    Chitosan-encapsulated K-10 nanoparticles
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Measurements

    particle size
    125 nm
    CK-10

    Source sentences

    Summary
    CK-10 nanoparticles with a particle size of 125 nm

    In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.

  3. 11LabNot a test of Kisspeptin-10 aloneIn vitro (cell-free)Other

    Chitosan-encapsulated K-10 (CK-10) nanoparticles had a zeta potential of 36.45 mV.

    In plain wordsIn lab tests, kisspeptin‑10 packed in chitosan nanoparticles gave a surface charge of 36.45 mV.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableCK-10 zeta potential
    Study

    n: not reported in source

    Chitosan-encapsulated K-10 nanoparticles
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Measurements

    zeta potential
    36.45 mV
    CK-10

    Source sentences

    Summary
    CK-10 nanoparticles with a particle size of 125 nm and a zeta potential of 36.45 mV were synthesized and compared with K-10.

    In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.

  4. 12LabNot a test of Kisspeptin-10 aloneIn vitro (cell-free)Other

    Chitosan nanoparticles showed 60% entrapment efficiency for K-10.

    In plain wordsIn lab tests, chitosan nanoparticles trapped 60% of the kisspeptin‑10.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableK-10 entrapment efficiency in chitosan nanoparticles
    Study

    n: not reported in source

    Chitosan nanoparticles
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Measurements

    entrapment efficiency
    60%
    K-10

    Source sentences

    Summary
    Chitosan nanoparticles showed 60% entrapment efficiency for K-10.

    In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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