In primary pituitary tumor cells from an X-LAG patient, pasireotide inhibited GH secretion, whereas octreotide did not.
In plain wordsIn cells from an X-LAG pituitary tumor, pasireotide inhibited growth hormone secretion, whereas octreotide did not.
- Peptide
- Pasireotide
- Outcome
- DecreaseGH secretion
- Study
humann: not reported in source
Primary pituitary tumor culture from an X-LAG syndrome patient- Comparator
- Octreotide
- Outcome group
- Growth hormone and IGF-1 · Endocrine and hormones
- Studied dose
- Dose not stated
Source sentences
Pasireotide, but not octreotide, inhibited GH secretion.
2 context sentences(design, population, supporting numbers)
We performed a series of hormonal profiles in a young female sporadic X-LAG syndrome patient and subsequently undertook in vitro studies of primary pituitary tumor culture following neurosurgical resection.
In vitro, the pituitary cells showed baseline GH and prolactin release that was further stimulated by GHRH administration.