Skip to content

Study · Not a test of the peptide alone · 2016

1 result

P53-Derived peptides conjugation to PEI: an approach to producing versatile and highly efficient targeted gene delivery carriers into cancer cells.

Mokhtarzadeh A, Parhiz H, Hashemi M, Abnous K, Ramezani M

Expert opinion on drug delivery8 Jan 2016Cited by 19 (Europe PMC)

PMID26654047 (opens in a new tab)DOI10.1517/17425247.2016.1126245 (opens in a new tab)PepBankPUB-26654047
Publisher pagePubMedAsk about this study
Jump to 1 result

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, PNC-27 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking PNC-27.

  1. 01LabNot a test of PNC-27 aloneIn vitro (cells)Activity measurement

    In cancer cells, conjugation of pooled PNC peptides to delivery vectors enhanced gene delivery with targeting exclusive to cancer cells.

    In plain wordsIn cells, vectors conjugated to pooled PNC peptides improved gene delivery with targeting exclusive to cancer cells.

    Peptide
    PNC-27
    Outcome
    IncreaseTargeted gene delivery
    Study

    n: not reported in source

    cancer cell lines
    Outcome group
    Formulation, delivery and stability · Cancer

    Source sentences

    Summary
    The results of gene delivery and shRNA-based gene silencing studies indicated that conjugation of PNC peptides could enhance gene delivery efficiently with high-targeted activity exclusively into cancer cells.
    2 context sentences
    Summary · context
    To overcome this problem and improve the specificity for cancer cells, we describe a new-targeted delivery system using p53-derived peptides, namely PNC 27 and PNC 28.
    Summary · context
    In transfection studies, three plasmids were used including luciferase, pEGFP and shRNA plasmid against Bcl-XL mRNA.

    In this study, PNC-27 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking PNC-27.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.