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Study · Animal study (in vivo) · drosophila melanogaster · 2016

2 results

In vivo high-resolution magic angle spinning magnetic and electron paramagnetic resonance spectroscopic analysis of mitochondria-targeted peptide in Drosophila melanogaster with trauma-induced thoracic injury.

Constantinou C, Apidianakis Y, Psychogios N, Righi V, Mindrinos MN, Khan N, Swartz HM, Szeto HH, Tompkins RG, Rahme LG, Tzika AA

International journal of molecular medicine8 Dec 2015Cited by 11 (Europe PMC)

PMID26648055 (opens in a new tab)PMCIDPMC4716799 (opens in a new tab)DOI10.3892/ijmm.2015.2426 (opens in a new tab)PepBankPUB-26648055
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In aged flies with trauma-induced thoracic injury, SS‑31 normalized the NMR spectral profile.

    In plain wordsIn injured flies, SS‑31 brought a chemical profile measured by NMR back to normal.

    Peptide
    Elamipretide (SS-31)
    Outcome
    Not applicableNMR spectral profile after trauma
    Study

    Drosophila melanogastern: not reported in source

    Aged flies with trauma-induced thoracic injury (needle puncture)
    Outcome group
    Mitochondrial function · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    A mitochondria-targeted compound, Szeto-Schiller (SS)-31 that promotes adenosine triphosphate (ATP) synthesis normalized the NMR spectral profile, as well as the mitochondrial redox status of the flies with trauma-induced thoracic injury, as assessed by EPR.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In aged flies with trauma-induced thoracic injury, SS‑31 normalized the mitochondrial redox status measured by EPR.

    In plain wordsIn injured flies, SS‑31 brought the mitochondrial oxidation state back to normal.

    Peptide
    Elamipretide (SS-31)
    Outcome
    Not applicableMitochondrial redox status (EPR) after trauma
    Study

    Drosophila melanogastern: not reported in source

    Aged flies with trauma-induced thoracic injury (needle puncture)
    Outcome group
    Mitochondrial function · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    A mitochondria-targeted compound, Szeto-Schiller (SS)-31 that promotes adenosine triphosphate (ATP) synthesis normalized the NMR spectral profile, as well as the mitochondrial redox status of the flies with trauma-induced thoracic injury, as assessed by EPR.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 08:19 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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