In girls with precocious puberty, adult height after quarterly triptorelin did not significantly differ from mid-parental height.
In plain wordsGirls receiving quarterly triptorelin reached adult heights similar to their mid-parental heights.
- Outcome
- No significant changeAdult height relative to mid-parental height
- Study
n = 13
- Comparator
- Mid-parental height
- Outcome group
- Linear growth · Endocrine and hormones
- Studied dose
- 11.25 mg/90 daysAs given in this study (human).
Measurements
- Adult height
- 157.1 cm
- quarterly triptorelin
- Mid-parental height
- 159.7 cm
- quarterly triptorelin group
Source sentences
The AH (157.1 ± 4.9 cm) of girls treated with quarterly triptorelin was not significantly different from their mid-parental height (159.7 ± 3.8 cm) and significantly increased in comparison with predicted AH (average tables) at the beginning of GnRH analog therapy.
2 context sentences(design, population, supporting numbers)
A group of girls with idiopathic CPP (n = 13; age 7.9 ± 0.6 years) were treated from the beginning with quarterly triptorelin (11.25 mg/90 days) and followed up to the achievement of adult height (AH).
A group of girls with idiopathic CPP (n = 12; age 8.0 ± 0.6 years) treated with monthly triptorelin (3.75 mg/28 days) served as controls.