In males with delayed puberty, a peak LH below 9.74 IU/L after GnRH stimulation gave moderate sensitivity and specificity for diagnosing hypogonadotropic hypogonadism.
In plain wordsIn boys and men with delayed puberty, a low LH peak after a gonadorelin test moderately well separated hypogonadotropic hypogonadism from other causes.
- Peptide
- Gonadorelin (GnRH, LHRH)
- Outcome
- Not applicableDiagnostic accuracy of peak LH after GnRH stimulation in males
- Study
n: not reported in source
- Outcome group
- Sex hormones and fertility · Endocrine and hormones
Measurements
- Sensitivity
- 80%
- peak LH <9.74 IU/L, males
- Specificity
- 86.4%
- peak LH <9.74 IU/L, males
Source sentences
The ROC curves indicated that a serum basal LH <0.6 IU/L or peak LH <9.74 IU/L resulted in moderate sensitivity (73.8% or 80.0%) and specificity (90.9% or 86.4%) in the diagnosis of HH in males.
2 context sentences(design, population, supporting numbers)
A study of 91 IHH, 27 CDP patients, 6 prepubertal children, and 20 pubertal adults was undertaken.
Blood samples were obtained at 0, 30, 60, and 120 min after GnRH administration and the levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were measured.
In this study, Gonadorelin (GnRH, LHRH) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Gonadorelin (GnRH, LHRH).