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Study · Randomized controlled trial · n = 220 · 2015

3 results

[Administering GnRH Agonists in the luteal phase of Artificial Cycle Frozen-Thawed Embryo Transfers. A prospective randomized study].

Gogce M, Benchaib M, Hadj S, Bordes A, du Menildot P, Lornage J, Salle B

Gynecologie, obstetrique & fertilite19 Aug 2015Cited by 5 (Europe PMC)

PMID26297156 (opens in a new tab)DOI10.1016/j.gyobfe.2015.07.005 (opens in a new tab)PepBankPUB-26297156
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In women undergoing frozen-thawed embryo transfer, added triptorelin did not significantly increase ongoing pregnancy versus usual progesterone supplementation.

    In plain wordsWomen receiving added triptorelin had no significant increase in ongoing pregnancy compared with usual progesterone supplementation.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeOngoing pregnancy
    Study

    n = 220

    Comparator
    Usual progesterone supplementation without added triptorelin
    Analysis
    Primary
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Two injections of 0.1mg · injectionAs given in this study (human).

    Measurements

    Ongoing pregnancy
    17%
    added triptorelin
    Ongoing pregnancy
    10.6%
    control

    Source sentences

    Summary
    The ongoing pregnancy rate was higher (17 % versus 10.6 % P=0.29) when triptorelin was added, although the difference wasn't significant for the population as a whole.
    2 context sentences
    Summary · context
    A prospective randomized controlled trial was conducted in a reproductive medicine center in a university hospital including all women starting an artificial cycle of Frozen-Thawed Embryo Transfers (FET).
    Summary · context
    In the addition of GnRh agonists' group, two triptorelin injections of 0.1mg were carried out on the 4th day and on the 6th day following the introduction of progesterone.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In women receiving day 2 embryos, added triptorelin increased ongoing pregnancy versus usual progesterone supplementation.

    In plain wordsWomen receiving day 2 embryos had more ongoing pregnancies with added triptorelin than with usual progesterone supplementation.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseOngoing pregnancy with day 2 embryos
    Study

    n: not reported in source

    Comparator
    Usual progesterone supplementation without added triptorelin
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Two injections of 0.1mg · injectionAs given in this study (human).

    Measurements

    Ongoing pregnancy
    34.6%
    added triptorelin
    Ongoing pregnancy
    10.3%
    control

    Source sentences

    Summary
    The increase proved to be significant in the case of day 2 embryos (34.6 % versus 10.3 % P<0.05) and of vitrified blastocysts (33.3% versus 12.5% P<0.05).
    3 context sentences
    Summary · context
    The ongoing pregnancy rate was higher (17 % versus 10.6 % P=0.29) when triptorelin was added, although the difference wasn't significant for the population as a whole.
    Summary · context
    A prospective randomized controlled trial was conducted in a reproductive medicine center in a university hospital including all women starting an artificial cycle of Frozen-Thawed Embryo Transfers (FET).
    Summary · context
    In the addition of GnRh agonists' group, two triptorelin injections of 0.1mg were carried out on the 4th day and on the 6th day following the introduction of progesterone.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In women receiving vitrified blastocysts, added triptorelin increased ongoing pregnancy versus usual progesterone supplementation.

    In plain wordsWomen receiving vitrified blastocysts had more ongoing pregnancies with added triptorelin than with usual progesterone supplementation.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseOngoing pregnancy with vitrified blastocysts
    Study

    n: not reported in source

    Comparator
    Usual progesterone supplementation without added triptorelin
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Two injections of 0.1mg · injectionAs given in this study (human).

    Measurements

    Ongoing pregnancy
    33.3%
    added triptorelin
    Ongoing pregnancy
    12.5%
    control

    Source sentences

    Summary
    The increase proved to be significant in the case of day 2 embryos (34.6 % versus 10.3 % P<0.05) and of vitrified blastocysts (33.3% versus 12.5% P<0.05).
    3 context sentences
    Summary · context
    The ongoing pregnancy rate was higher (17 % versus 10.6 % P=0.29) when triptorelin was added, although the difference wasn't significant for the population as a whole.
    Summary · context
    A prospective randomized controlled trial was conducted in a reproductive medicine center in a university hospital including all women starting an artificial cycle of Frozen-Thawed Embryo Transfers (FET).
    Summary · context
    In the addition of GnRh agonists' group, two triptorelin injections of 0.1mg were carried out on the 4th day and on the 6th day following the introduction of progesterone.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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