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Study · Not a test of the peptide alone · 2015

2 results

Distinct actin oligomers modulate differently the activity of actin nucleators.

Qu Z, Silvan U, Jockusch BM, Aebi U, Schoenenberger CA, Mannherz HG

The FEBS journal11 Aug 2015Cited by 11 (Europe PMC)

PMID26194975 (opens in a new tab)DOI10.1111/febs.13381 (opens in a new tab)PepBankPUB-26194975
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 01LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cell-free)Mechanism

    In vitro, crosslinked upper dimer and trimer actin oligomers stimulated repolymerization of actin from actin:Tβ4 complexes.

    In plain wordsIn lab tests, some actin oligomers stimulated actin to build filaments again from complexes with Tβ4.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseRepolymerization of actin from actin:Tβ4 complexes by UD and trimer
    Study

    n: not reported in source

    purified crosslinked actin oligomers and actin:Tβ4 complexes
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    UD and trimer stimulated the repolymerization of actin from complexes with thymosin β4 (Tβ4) or profilin
    1 context sentence
    Summary · context
    Therefore we used chemically crosslinked actin oligomers to analyse their effect on actin polymerization.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  2. 02LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cell-free)Mechanism

    In vitro, the lower actin dimer did not stimulate repolymerization from the actin:Tβ4 complex, though it did from the profilin:actin complex.

    In plain wordsIn lab tests, the lower actin dimer did not restart actin filament building from complexes with Tβ4.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeRepolymerization of actin from actin:Tβ4 complex by LD
    Study

    n: not reported in source

    purified crosslinked actin oligomers and actin:Tβ4 complexes
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    whereas the LD stimulated repolymerization only from the profilin : actin but not the actin : Tβ4 complex.
    1 context sentence
    Summary · context
    Therefore we used chemically crosslinked actin oligomers to analyse their effect on actin polymerization.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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