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Study · Observational study · n = 471 · 2015

2 results

Predictive parameters of response to desmopressin in primary nocturnal enuresis.

Van Herzeele C, Evans J, Eggert P, Lottmann H, Norgaard JP, Vande Walle J

Journal of pediatric urology21 May 2015Cited by 30 (Europe PMC)

PMID26059526 (opens in a new tab)DOI10.1016/j.jpurol.2015.03.007 (opens in a new tab)PepBankPUB-26059526
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanObservational studyOther

    In children with primary nocturnal enuresis, age was the only demographic variable that significantly predicted desmopressin response.

    In plain wordsIn children with bedwetting, age was the only demographic factor linked to desmopressin response.

    Peptide
    Desmopressin
    Outcome
    Not applicablePredictors of desmopressin response
    Study

    n = 471

    Analysis
    Secondary
    Outcome group
    Urinary continence and bladder function · Kidney and urinary
    Studied dose
    Dose not stated · oral · ≤6 monthsAs given in this study (human).

    Source sentences

    Summary
    Of the demographic variables, age was the only significant predictor for response to desmopressin.
    2 context sentences
    Summary · context
    This study is a re-analysis of a prospective, open-label, multinational, phase-IV study evaluating ≤6 months of treatment with desmopressin tablets for children with primary nocturnal enuresis.
    Summary · context
    Of these, 471 children completed the study with 6 months follow-up and recording in a frequency/volume chart.
  2. 02HumanObservational studyOther

    In children with primary nocturnal enuresis, weekly wet nights, average and maximum daytime voided volumes, daytime diuresis, nocturnal diuresis, maximum 24-hour voided volume and total 24-hour diuresis predicted desmopressin response after age adjustment.

    In plain wordsIn children with bedwetting, several urine diary measures were linked to desmopressin response after age adjustment.

    Peptide
    Desmopressin
    Outcome
    Not applicableAge-adjusted predictors of desmopressin response
    Study

    n = 471

    Analysis
    Secondary
    Outcome group
    Urinary continence and bladder function · Kidney and urinary
    Studied dose
    Dose not stated · oral · ≤6 monthsAs given in this study (human).

    Source sentences

    Summary
    Controlling for age, the significant predictive variables were: number of wet nights a week, average voided volume daytime, maximum voided volume daytime, total daytime diuresis, nocturnal diuresis (see Figure), maximum voided volume 24 h and total 24 h diuresis.
    2 context sentences
    Summary · context
    This study is a re-analysis of a prospective, open-label, multinational, phase-IV study evaluating ≤6 months of treatment with desmopressin tablets for children with primary nocturnal enuresis.
    Summary · context
    Of these, 471 children completed the study with 6 months follow-up and recording in a frequency/volume chart.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Registered trials1

Trials this study reports on, or that list this study as a reference. Registry data from ClinicalTrials.gov.

1 trial · 1 completed · source ClinicalTrials.gov (opens in a new tab)

CompletedPhase 4NCT00245479

A Study of Oral Desmopressin in Previously Untreated Children Aged 5 to 15 Years With Primary Nocturnal Enuresis

Ferring Pharmaceuticalsn = 802Apr 2002 to Nov 2006

Nocturnal Enuresis

Trial pageClinicalTrials.govUpdated 19 May 2011

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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