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Study · Not a test of the peptide alone · 2015

2 results

Rational design of triazololipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotropins.

Beltramo M, Robert V, Galibert M, Madinier JB, Marceau P, Dardente H, Decourt C, De Roux N, Lomet D, Delmas AF, Caraty A, Aucagne V

Journal of medicinal chemistry13 Apr 2015Cited by 33 (Europe PMC)

PMID25811530 (opens in a new tab)DOI10.1021/jm5019675 (opens in a new tab)PepBankPUB-25811530
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Kisspeptin-10.

  1. 01AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Efficacy outcome

    In ewes with a quiescent reproductive system, the best triazololipopeptide analog of kisspeptin‑10 induced a much longer increase in luteinizing hormone release than KP10.

    In plain wordsIn ewes, a modified kisspeptin compound raised luteinizing hormone for much longer than KP10 did.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseLuteinizing hormone release
    Study

    sheepn: not reported in source

    ewes with a quiescent reproductive system
    Comparator
    KP10
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    When injected in ewes with a quiescent reproductive system, the best compound of our series induced a much prolonged increase of luteinizing hormone release compared to KP10 and increased follicle-stimulating hormone plasma concentration.

    In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.

  2. 02AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Efficacy outcome

    In ewes with a quiescent reproductive system, the best triazololipopeptide analog of kisspeptin‑10 increased follicle-stimulating hormone plasma concentration.

    In plain wordsIn ewes, a modified kisspeptin compound raised follicle-stimulating hormone in the blood.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseFollicle-stimulating hormone plasma concentration
    Study

    sheepn: not reported in source

    ewes with a quiescent reproductive system
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    When injected in ewes with a quiescent reproductive system, the best compound of our series induced a much prolonged increase of luteinizing hormone release compared to KP10 and increased follicle-stimulating hormone plasma concentration.

    In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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