In human umbilical vein endothelial cells, kisspeptin‑10 increased migration at lower concentrations, especially 100 nM, and reduced it at the higher concentration.
In plain wordsIn lab-grown vein cells, a lower kisspeptin‑10 dose raised cell movement and a higher dose lowered it.
- Peptide
- Kisspeptin-10
- Outcome
- MixedEndothelial cell migration
- Study
humann: not reported in source
HUVEC (human umbilical vein endothelial cells)- Comparator
- Untreated cells
- Outcome group
- Tumor growth · Cardiovascular
- Studied dose
- 10-100 or 500 nM · 24 hoursAs given in this study (human).
Source sentences
Migration and proliferation of endothelial cells were increased at lower concentration of kp-10 specially at 100 nM while higher concentration reduced both migration and proliferation.
1 context sentence(design, population, supporting numbers)
We compared migration of Human Umbilical Vein Endothelial Cells (HUVECs) were treated with 10-100 or 500 nM kp-10 for 24 hours and no treated cells using an in vitro trans membrane migration assay and HUVEC proliferation of treated endothelial cells with 10-100 or 500 nM kp-10 for 48 hours and no tr…