Gonadotropin-releasing hormone agonist triggering is effective, even at a low dose, for final oocyte maturation in ART cycles: Case series.

Gülekli B, Göde F, Sertkaya Z, Işık AZ

Journal of the Turkish German Gynecological Association1 Mar 2015Cited by 4 (Europe PMC)

PMID25788848PMCIDPMC4358310DOI10.5152/jtgga.2015.15084PepBankPUB-25788848

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study13

13 results from studies that gave the peptide. 13 results from people.

01HumanObservational studyEfficacy outcome
In fresh ART cycles, retrieved mature oocyte counts did not differ significantly between low-dose and standard-dose triptorelin triggering.
In plain wordsIn women undergoing fertility treatment, mature egg counts did not differ significantly between low-dose and standard-dose triptorelin.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeRetrieved mature oocytes versus standard dose
Study
n: not reported in source
Comparator
0.2 mg triptorelin
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Source sentences
Summary
On comparison of the results of these patients (fresh cycles; n=7) with those of matched controls, there were no significant differences in terms of retrieved mature oocytes, implantation rates, or clinical pregnancy rates (p>0.05).
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884811
02HumanObservational studyEfficacy outcome
In fresh ART cycles, implantation rates did not differ significantly between low-dose and standard-dose triptorelin triggering.
In plain wordsIn women undergoing fertility treatment, implantation rates did not differ significantly between low-dose and standard-dose triptorelin.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeImplantation rate versus standard dose
Study
n: not reported in source
Comparator
0.2 mg triptorelin
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Source sentences
Summary
On comparison of the results of these patients (fresh cycles; n=7) with those of matched controls, there were no significant differences in terms of retrieved mature oocytes, implantation rates, or clinical pregnancy rates (p>0.05).
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884812
03HumanObservational studyEfficacy outcome
In fresh ART cycles, clinical pregnancy rates did not differ significantly between low-dose and standard-dose triptorelin triggering.
In plain wordsIn women undergoing fertility treatment, pregnancy rates did not differ significantly between low-dose and standard-dose triptorelin.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeClinical pregnancy rate versus standard dose
Study
n: not reported in source
Comparator
0.2 mg triptorelin
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Source sentences
Summary
On comparison of the results of these patients (fresh cycles; n=7) with those of matched controls, there were no significant differences in terms of retrieved mature oocytes, implantation rates, or clinical pregnancy rates (p>0.05).
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884813
04HumanCase report or seriesEfficacy outcome
In women undergoing ART with triptorelin triggering, the mean retrieved oocyte count was 15.66±7.82.
In plain wordsIn women undergoing fertility treatment, low-dose triptorelin triggering yielded a mean of 15.66 retrieved eggs.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicableRetrieved oocytes
Study
n = 9
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Measurements
Retrieved oocytes
15.66 oocytes
triptorelin 0.1 mg trigger
Source sentences
Summary
The mean (±) numbers of retrieved, metaphase II, and fertilized oocytes were 15.66±7.82, 14±7.28, and 10.11±5.86, respectively.
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884801
05HumanCase report or seriesEfficacy outcome
In women undergoing ART with triptorelin triggering, the mean metaphase II oocyte count was 14±7.28.
In plain wordsIn women undergoing fertility treatment, low-dose triptorelin triggering yielded a mean of 14 mature eggs.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicableMetaphase II oocytes
Study
n = 9
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Measurements
Metaphase II oocytes
14 oocytes
triptorelin 0.1 mg trigger
Source sentences
Summary
The mean (±) numbers of retrieved, metaphase II, and fertilized oocytes were 15.66±7.82, 14±7.28, and 10.11±5.86, respectively.
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884802
06HumanCase report or seriesEfficacy outcome
In women undergoing ART with triptorelin triggering, the mean fertilized oocyte count was 10.11±5.86.
In plain wordsIn women undergoing fertility treatment, low-dose triptorelin triggering yielded a mean of 10.11 fertilized eggs.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicableFertilized oocytes
Study
n = 9
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Measurements
Fertilized oocytes
10.11 oocytes
triptorelin 0.1 mg trigger
Source sentences
Summary
The mean (±) numbers of retrieved, metaphase II, and fertilized oocytes were 15.66±7.82, 14±7.28, and 10.11±5.86, respectively.
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884803
07HumanCase report or seriesSafety outcome
No ovarian hyperstimulation syndrome occurred in women receiving low-dose triptorelin triggering.
In plain wordsNo ovarian hyperstimulation syndrome occurred in women receiving low-dose triptorelin triggering.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicableOvarian hyperstimulation syndrome
Study
n = 9
Outcome group
Adverse events · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Source sentences
Summary
No case of OHSS was encountered.
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884810
08HumanCase report or seriesEfficacy outcome
In women undergoing ART with low-dose triptorelin triggering, implantation rate was 46.1%.
In plain wordsIn women undergoing fertility treatment with low-dose triptorelin triggering, implantation rate was 46.1%.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicableImplantation rate
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Measurements
Implantation rate
46.1%
triptorelin 0.1 mg trigger
Source sentences
Summary
The implantation and clinical pregnancy rates were 46.1% and 71.4%, respectively.
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884804
09HumanCase report or seriesEfficacy outcome
In women undergoing ART with low-dose triptorelin triggering, clinical pregnancy rate was 71.4%.
In plain wordsIn women undergoing fertility treatment with low-dose triptorelin triggering, clinical pregnancy rate was 71.4%.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicableClinical pregnancy rate
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Measurements
Clinical pregnancy rate
71.4%
triptorelin 0.1 mg trigger
Source sentences
Summary
The implantation and clinical pregnancy rates were 46.1% and 71.4%, respectively.
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884805
10HumanCase report or seriesEfficacy outcome
Among pregnancies after low-dose triptorelin triggering, the abstract reported 2 live births.
In plain wordsAfter low-dose triptorelin triggering in women, the abstract reported 2 live births.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicableLive births
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Measurements
Live births
2 pregnancies
triptorelin 0.1 mg trigger
Source sentences
Summary
Of the pregnancies, 2 were live births, 1 was a preterm birth (twins), 2 are on-going, and 2 ended as miscarriages.
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884806
11HumanCase report or seriesSafety outcome
Among pregnancies after low-dose triptorelin triggering, the abstract reported 1 preterm twin birth.
In plain wordsAfter low-dose triptorelin triggering in women, the abstract reported 1 preterm twin birth.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicablePreterm twin birth
Study
n: not reported in source
Outcome group
Adverse events · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Measurements
Preterm births
1 pregnancies
triptorelin 0.1 mg trigger
Source sentences
Summary
Of the pregnancies, 2 were live births, 1 was a preterm birth (twins), 2 are on-going, and 2 ended as miscarriages.
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884807
12HumanCase report or seriesEfficacy outcome
Among pregnancies after low-dose triptorelin triggering, 2 were ongoing.
In plain wordsAfter low-dose triptorelin triggering in women, 2 pregnancies were ongoing.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicableOngoing pregnancies
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Measurements
Ongoing pregnancies
2 pregnancies
triptorelin 0.1 mg trigger
Source sentences
Summary
Of the pregnancies, 2 were live births, 1 was a preterm birth (twins), 2 are on-going, and 2 ended as miscarriages.
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884808
13HumanCase report or seriesSafety outcome
Among pregnancies after low-dose triptorelin triggering, 2 ended in miscarriage.
In plain wordsAfter low-dose triptorelin triggering in women, 2 pregnancies ended in miscarriage.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicableMiscarriages
Study
n: not reported in source
Outcome group
Adverse events · Reproductive and sexual health
Studied dose
0.1 mgAs given in this study (human).
Measurements
Miscarriages
2 pregnancies
triptorelin 0.1 mg trigger
Source sentences
Summary
Of the pregnancies, 2 were live births, 1 was a preterm birth (twins), 2 are on-going, and 2 ended as miscarriages.
2 context sentences(design, population, supporting numbers)
Summary · context
Nine females undergoing ovarian stimulation in a GnRH antagonist protocol who received triptorelin 0.1 mg to trigger final oocyte maturation were included.
Summary · context
Treatment outcomes of these patients were compared with those of controls, matched for age and oocyte number (n=14), who received 0.2 mg triptorelin at the same time.
Report a problemFND-2578884809

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
22 Oct 2026, 02:26 UTC
Study results updated
Version 1
21 Oct 2026, 18:59 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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Keywords

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