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Study · Not a test of the peptide alone · 2015

1 result

Transplantation of bovine adrenocortical cells encapsulated in alginate.

Balyura M, Gelfgat E, Ehrhart-Bornstein M, Ludwig B, Gendler Z, Barkai U, Zimerman B, Rotem A, Block NL, Schally AV, Bornstein SR

Proceedings of the National Academy of Sciences of the United States of America9 Feb 2015Cited by 42 (Europe PMC)

PMID25675525 (opens in a new tab)PMCIDPMC4345555 (opens in a new tab)DOI10.1073/pnas.1500242112 (opens in a new tab)PepBankPUB-25675525
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  1. 01LabNot a test of Triptorelin (Trelstar, Decapeptyl) aloneIn vitro (cells)Mechanism

    In bovine adrenocortical cells, alginate encapsulation improved responsiveness to the LHRH agonist [D-Trp6]LHRH compared with monolayer culture.

    In plain wordsIn cells, alginate encapsulation improved responses to triptorelin compared with monolayer culture.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseResponse to LHRH agonist
    Study

    bovinen: not reported in source

    Bovine adrenocortical cells
    Comparator
    Monolayer culture
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Source sentences

    Summary
    Encapsulation also improved significantly both the capacity of adrenal cells for stable, long-term basal hormone release as well as the response to pituitary adrenocorticotropic hormone (ACTH) and hypothalamic luteinizing hormone-releasing hormone (LHRH) agonist, [D-Trp6]LHRH.
    2 context sentences
    Summary · context
    We found that, compared with BACs in monolayer culture, encapsulation in alginate significantly increased the life span of BACs.
    Summary · context
    We created a bioartificial adrenal with 3D cell culture conditions by encapsulation of bovine adrenocortical cells (BACs) in alginate (enBACs).

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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