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Study · Not a test of the peptide alone · 2015

3 results

Impact of BMI on gonadorelin-stimulated LH peak in premenarcheal girls with idiopathic central precocious puberty.

Fu JF, Liang JF, Zhou XL, Prasad HC, Jin JH, Dong GP, Rose SR

Obesity (Silver Spring, Md.)3 Feb 2015Cited by 26 (Europe PMC)

PMID25645648 (opens in a new tab)DOI10.1002/oby.21010 (opens in a new tab)PepBankPUB-25645648
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Gonadorelin (GnRH, LHRH) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Gonadorelin (GnRH, LHRH).

  1. 01HumanNot a test of Gonadorelin (GnRH, LHRH) aloneObservational studyOther

    In girls with idiopathic central precocious puberty, the peak LH/FSH ratio after GnRH stimulation was lower in obese girls than in normal-weight and overweight girls.

    In plain wordsIn girls with early puberty, obese girls had a lower LH to FSH ratio in a gonadorelin test than normal-weight and overweight girls.

    Peptide
    Gonadorelin (GnRH, LHRH)
    Outcome
    DecreasePeak LH/FSH ratio after GnRH, obese versus others
    Study

    n = 865

    Comparator
    Normal-weight and overweight girls with ICPP
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Measurements

    Median peak LH/FSH ratio
    0.6 ratio
    obese
    Median peak LH/FSH ratio
    0.8 ratio
    normal weight
    Median peak LH/FSH ratio
    0.8 ratio
    overweight

    Source sentences

    Summary
    Peak LH/FSH ratio was also lower in the obese group (median 0.6, interquartile 0.68-0.90) compared with the normal-weight (median 0.8, interquartile 0.61-1.11) and overweight (median 0.8, interquartile 0.64-0.92) groups.
    1 context sentence
    Summary · context
    Retrospective single-center cohort study was carried out in 865 confirmed ICPP girls who underwent GnRH stimulation tests.

    In this study, Gonadorelin (GnRH, LHRH) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Gonadorelin (GnRH, LHRH).

  2. 02HumanNot a test of Gonadorelin (GnRH, LHRH) aloneObservational studyOther

    In girls with idiopathic central precocious puberty, peak LH after GnRH stimulation was lower in overweight girls than in normal-weight girls.

    In plain wordsIn girls with early puberty, overweight girls had a lower LH peak in a gonadorelin test than normal-weight girls.

    Peptide
    Gonadorelin (GnRH, LHRH)
    Outcome
    DecreasePeak LH after GnRH, overweight versus normal weight
    Study

    n: not reported in source

    Comparator
    Normal-weight girls with ICPP
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Measurements

    Median peak LH
    9.1 mIU/mL
    normal weight
    Median peak LH
    8.5 mIU/mL
    overweight

    Source sentences

    Summary
    Peak LH levels after GnRH were much higher in the normal-weight group, with a median of 9.1 mIU ml(-1) (interquartile 5.2-13.1), compared with the median peak LH in the overweight and obese groups (8.5 mIU ml(-1), interquartile 5.3-11.6, and 6.2 mIU ml(-1), interquartile 5.3-11.0, respectively P < 0…
    1 context sentence
    Summary · context
    Retrospective single-center cohort study was carried out in 865 confirmed ICPP girls who underwent GnRH stimulation tests.

    In this study, Gonadorelin (GnRH, LHRH) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Gonadorelin (GnRH, LHRH).

  3. 03HumanNot a test of Gonadorelin (GnRH, LHRH) aloneObservational studyOther

    In girls with idiopathic central precocious puberty, peak LH after GnRH stimulation was lower in obese girls than in normal-weight girls.

    In plain wordsIn girls with early puberty, obese girls had a lower LH peak in a gonadorelin test than normal-weight girls.

    Peptide
    Gonadorelin (GnRH, LHRH)
    Outcome
    DecreasePeak LH after GnRH, obese versus normal weight
    Study

    n: not reported in source

    Comparator
    Normal-weight girls with ICPP
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Measurements

    Median peak LH
    9.1 mIU/mL
    normal weight
    Median peak LH
    6.2 mIU/mL
    obese

    Source sentences

    Summary
    Peak LH levels after GnRH were much higher in the normal-weight group, with a median of 9.1 mIU ml(-1) (interquartile 5.2-13.1), compared with the median peak LH in the overweight and obese groups (8.5 mIU ml(-1), interquartile 5.3-11.6, and 6.2 mIU ml(-1), interquartile 5.3-11.0, respectively P < 0…
    1 context sentence
    Summary · context
    Retrospective single-center cohort study was carried out in 865 confirmed ICPP girls who underwent GnRH stimulation tests.

    In this study, Gonadorelin (GnRH, LHRH) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Gonadorelin (GnRH, LHRH).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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