In rats with experimental endometriosis, triptorelin pamoate significantly reduced weight of the assessed tissue.
In plain wordsIn rats with endometriosis, triptorelin significantly reduced the weight of the assessed tissue.
- Outcome
- DecreaseWeight reduction
- Study
ratn: not reported in source
Wistar rats with subcutaneous endometriosis- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
- Studied dose
- 0.18 or 0.56 mg/kg · subcutaneousAs given in this study (rat).
Source sentences
Weight reduction was also significant in the triptorelin pamoate and the acetylsalicylic acid groups.
3 context sentences(design, population, supporting numbers)
The relative dry and wet weights of the endometrioma were used to evaluate response to the drug.
Fifty three-month-old female Wistar rats (Rattus norvergicus) were distributed into one control group and four treatment groups: estradiol (2.5; 5; 10 mg/kg s.c.), medroxyprogesterone acetate (0.5; 2; 5 mg/kg s.c.), triptorelin pamoate (0.18; 0.56 mg/kg s.c.) and acetylsalicylic acid (3 mg/kg per os).
Treatments were administered between day 5 and day 14.