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Study · Non-randomized trial · n = 64 · 2014

4 results

[New possibilities of pharmacological treatment of adult epilepsy].

Belskaya GN, Ponomareva IV

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova1 Jan 2014

PMID25591518 (opens in a new tab)PepBankPUB-25591518
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In patients with epilepsy, seizure frequency decreased significantly during adjunctive cortexin treatment.

    In plain wordsIn patients with epilepsy, seizures became less frequent during cortexin treatment with standard therapy.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    DecreaseSeizure frequency
    Study

    n = 64

    Outcome group
    Seizures · Nervous system and cognition
    Studied dose
    10 mg daily · intramuscular · Three 10-day courses during 12 monthsAs given in this study (human).

    Source sentences

    Summary
    There were the significant decrease in the frequency of seizures
    2 context sentences
    Summary · context
    A study included 64 patients with epilepsy (22 men and 42 women, aged from 20 to 85 years).
    Summary · context
    Along with standard treatment, the patients received cortexin (three 10-day courses during 12 months intramuscular in dose 10 mg daily).
  2. 02HumanNon-randomized trialEfficacy outcome

    In patients with epilepsy receiving adjunctive cortexin, no failure of remission was reported.

    In plain wordsIn patients with epilepsy receiving cortexin with standard therapy, no loss of remission was reported.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    Not applicableFailure of remission
    Study

    n = 64

    Outcome group
    Seizures · Nervous system and cognition
    Studied dose
    10 mg daily · intramuscular · Three 10-day courses during 12 monthsAs given in this study (human).

    Source sentences

    Summary
    the absence of failure of remission
    2 context sentences
    Summary · context
    A study included 64 patients with epilepsy (22 men and 42 women, aged from 20 to 85 years).
    Summary · context
    Along with standard treatment, the patients received cortexin (three 10-day courses during 12 months intramuscular in dose 10 mg daily).
  3. 03HumanNon-randomized trialEfficacy outcome

    In patients with epilepsy, electroencephalographic patterns improved during adjunctive cortexin treatment.

    In plain wordsIn patients with epilepsy, brain electrical patterns improved during cortexin treatment with standard therapy.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    IncreaseElectroencephalographic pattern
    Study

    n = 64

    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    10 mg daily · intramuscular · Three 10-day courses during 12 monthsAs given in this study (human).

    Source sentences

    Summary
    the positive dynamics of electroencephalographic pattern
    2 context sentences
    Summary · context
    A study included 64 patients with epilepsy (22 men and 42 women, aged from 20 to 85 years).
    Summary · context
    Along with standard treatment, the patients received cortexin (three 10-day courses during 12 months intramuscular in dose 10 mg daily).
  4. 04HumanNon-randomized trialEfficacy outcome

    In patients with epilepsy, adjunctive cortexin treatment coincided with cessation of the listed neurological, mood, and hypertension symptoms.

    In plain wordsIn patients with epilepsy, the listed symptoms stopped during cortexin treatment with standard therapy.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    DecreaseConcomitant symptoms
    Study

    n = 64

    Outcome group
    Overall treatment effect · Nervous system and cognition
    Studied dose
    10 mg daily · intramuscular · Three 10-day courses during 12 monthsAs given in this study (human).

    Source sentences

    Summary
    as well as stopping of such symptoms as headache, non-systemic vertigo, asthenia, cognitive impairment, anxiety and depression, arterial hypertension.
    2 context sentences
    Summary · context
    A study included 64 patients with epilepsy (22 men and 42 women, aged from 20 to 85 years).
    Summary · context
    Along with standard treatment, the patients received cortexin (three 10-day courses during 12 months intramuscular in dose 10 mg daily).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:25 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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