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Study · Ex vivo tissue · 2014

2 results

[Sensitivity of patients to immunomodulators in immunodeficiency diseases].

Stasenko AA, Zhulaĭ VV, Novopol'tseva IIu, Dontsova LS, Zaiats NV, Negievich VI

Klinichna khirurhiia1 Aug 2014Cited by 1 (Europe PMC)

PMID25417290 (opens in a new tab)PepBankPUB-25417290
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In blood neutrophils from patients with viral infections, sensitivity to immunofan and timalin was greatest among the tested immunomodulators.

    In plain wordsIn lab tests of viral-infection blood samples, neutrophils were most sensitive to immunofan and timalin.

    Peptide
    Thymalin
    Outcome
    Not applicableNeutrophil sensitivity
    Study

    humann: not reported in source

    Blood neutrophils from patients with viral infections
    Comparator
    Other tested immunomodulators
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In patients, suffering viral infections, the blood neutrophils are mostly sensitive to immunofan and timalin.

Studies that did not test the peptide alone1

In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymogen (oglufanide).

  1. 02LabNot a test of Thymogen (oglufanide) aloneEx vivo tissueActivity measurement

    In some patients, persistently preactivated blood neutrophils showed reduced responsiveness to immunomodulators, which included timogen.

    In plain wordsIn lab tests, some patients' preactivated blood neutrophils showed reduced responses to immunomodulators, including timogen.

    Peptide
    Thymogen (oglufanide)
    Outcome
    DecreaseReduced neutrophil responsiveness to immunomodulators
    Study

    humann: not reported in source

    Blood neutrophils from patients with immunodeficient diseases
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Absence of sensitivity of the blood neutrophils towards activating stimuli (immunomodulators) in some patients was caused by a phenomenon, according to which the blood neutrophils, persisting durably in a preactivated state, further (while examining of the patients) have a reduced capacity for answering to stimulation.
    1 context sentence
    Summary · context
    There were examined 198 patients, in whom immunodeficient (inflammatory, infectious and viral) diseases were revealed, as well as 10 healthy persons--for investigation of sensitivity of the blood neutrophils to immunomodulators (timalin, immunofan, polyoxidonium, timogen, erbisol).

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 12:50 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    14 Oct 2026, 05:02 UTC

    Study results updated

  3. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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