[An open clinical trial of cortexin in treatment of brain ischemia].

Mashin VV, Belova LA, Chaplanova OI, Khusnullina AF, Manasian AM

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova1 Jan 2014Cited by 1 (Europe PMC)

PMID25403301PepBankPUB-25403301

Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

01HumanNon-randomized trialEfficacy outcome
In patients with brain ischemia, cortexin treatment coincided with decreased or fully regressed focal neurological symptoms.
In plain wordsIn patients with brain ischemia, focal neurological symptoms decreased or disappeared during cortexin treatment.
Peptide
Cortexin (cortical polypeptide complex)
Outcome
DecreaseFocal neurological symptoms
Study
n = 500
Outcome group
Overall treatment effect · Nervous system and cognition
Studied dose
10 mg/day · 10 daysAs given in this study (human).
Source sentences
Summary
A decrease or complete regression of focal neurological symptoms, positive changes in indicators of cognitive impairment, normalization of emotional status and decrease in depression level were noted during the treatment.
2 context sentences(design, population, supporting numbers)
Summary · context
All patients received cortexin in dose 10 mg/day during 10 days.
Summary · context
We analyzed treatment results for 500 patients with BI, stage II, mean age 63,7 ± 10,23 years.
Report a problemFND-2540330101
02HumanNon-randomized trialEfficacy outcome
In patients with brain ischemia, cognitive impairment indicators improved during cortexin treatment.
In plain wordsIn patients with brain ischemia, cognitive impairment measures improved during cortexin treatment.
Peptide
Cortexin (cortical polypeptide complex)
Outcome
IncreaseCognitive impairment indicators
Study
n = 500
Outcome group
Cognition and memory · Nervous system and cognition
Studied dose
10 mg/day · 10 daysAs given in this study (human).
Source sentences
Summary
A decrease or complete regression of focal neurological symptoms, positive changes in indicators of cognitive impairment, normalization of emotional status and decrease in depression level were noted during the treatment.
2 context sentences(design, population, supporting numbers)
Summary · context
All patients received cortexin in dose 10 mg/day during 10 days.
Summary · context
We analyzed treatment results for 500 patients with BI, stage II, mean age 63,7 ± 10,23 years.
Report a problemFND-2540330102
03HumanNon-randomized trialEfficacy outcome
In patients with brain ischemia, emotional status normalized during cortexin treatment.
In plain wordsIn patients with brain ischemia, emotional status normalized during cortexin treatment.
Peptide
Cortexin (cortical polypeptide complex)
Outcome
IncreaseEmotional status
Study
n = 500
Outcome group
Anxiety and mood · Mental health and mood
Studied dose
10 mg/day · 10 daysAs given in this study (human).
Source sentences
Summary
A decrease or complete regression of focal neurological symptoms, positive changes in indicators of cognitive impairment, normalization of emotional status and decrease in depression level were noted during the treatment.
2 context sentences(design, population, supporting numbers)
Summary · context
All patients received cortexin in dose 10 mg/day during 10 days.
Summary · context
We analyzed treatment results for 500 patients with BI, stage II, mean age 63,7 ± 10,23 years.
Report a problemFND-2540330103
04HumanNon-randomized trialEfficacy outcome
In patients with brain ischemia, depression levels decreased during cortexin treatment.
In plain wordsIn patients with brain ischemia, depression decreased during cortexin treatment.
Peptide
Cortexin (cortical polypeptide complex)
Outcome
DecreaseDepression level
Study
n = 500
Outcome group
Anxiety and mood · Mental health and mood
Studied dose
10 mg/day · 10 daysAs given in this study (human).
Source sentences
Summary
A decrease or complete regression of focal neurological symptoms, positive changes in indicators of cognitive impairment, normalization of emotional status and decrease in depression level were noted during the treatment.
2 context sentences(design, population, supporting numbers)
Summary · context
All patients received cortexin in dose 10 mg/day during 10 days.
Summary · context
We analyzed treatment results for 500 patients with BI, stage II, mean age 63,7 ± 10,23 years.
Report a problemFND-2540330104

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
22 Oct 2026, 02:25 UTC
Study results updated
Version 1
21 Oct 2026, 18:59 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

MeSH terms

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