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Study · Measured the body's own peptide · 2015

1 result

H2O2 Exposure Affects Myotube Stiffness and Actin Filament Polymerization.

Wong SW, Sun S, Cho M, Lee KK, Mak AF

Annals of biomedical engineering5 Nov 2014Cited by 16 (Europe PMC)

PMID25371376 (opens in a new tab)DOI10.1007/s10439-014-1178-2 (opens in a new tab)PepBankPUB-25371376
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Mechanism

    In cultured murine C2C12 myotubes, prolonged H2O2 exposure was associated with lower expression of the body's own thymosin beta‑4.

    In plain wordsIn cells, long H2O2 exposure went with lower levels of the cells' own thymosin beta‑4.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    DecreaseThymosin beta 4 expression after prolonged H2O2 exposure
    Study

    mousen: not reported in source

    C2C12 myotubes
    Outcome group
    Receptor activity and mechanism · Musculoskeletal

    Source sentences

    Summary
    Such depolymerization effect was associated with the down-regulation of thymosin beta 4, as well as the up-regulation of both cofilin2 and profilin1 after prolong H2O2 treatments.
    1 context sentence
    Summary · context
    H2O2 was applied as an extrinsic oxidant to C2C12 myotubes.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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