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Study · Animal study (in vivo) · pig · 2015

3 results

Experimental coronary artery stenosis accelerates kidney damage in renovascular hypertensive swine.

Sun D, Eirin A, Zhu XY, Zhang X, Crane JA, Woollard JR, Lerman A, Lerman LO

Kidney international22 Oct 2014Cited by 12 (Europe PMC)

PMID25337776 (opens in a new tab)PMCIDPMC4382395 (opens in a new tab)DOI10.1038/ki.2014.343 (opens in a new tab)PepBankPUB-25337776
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In pigs with coronary artery stenosis, Bendavia decreased oxidative stress.

    In plain wordsIn pigs with a narrowed heart artery, Bendavia lowered oxidative stress.

    Peptide
    Elamipretide (SS-31)
    Outcome
    DecreaseOxidative stress in CAS
    Study

    pign: not reported in source

    Swine with coronary artery stenosis (CAS)
    Outcome group
    Oxidative stress · Kidney and urinary
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Bendavia, a mitochondria-targeted peptide, decreased oxidative stress and improved renal function and structure in CAS.
    1 context sentence
    Summary · context
    Pigs (seven each) were assigned to sham, left-circumflex CAS, renovascular HT, and CAS plus HT groups.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In pigs with coronary artery stenosis, Bendavia improved renal function.

    In plain wordsIn pigs with a narrowed heart artery, Bendavia improved kidney function.

    Peptide
    Elamipretide (SS-31)
    Outcome
    IncreaseRenal function in CAS
    Study

    pign: not reported in source

    Swine with coronary artery stenosis (CAS)
    Outcome group
    Kidney function · Kidney and urinary
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Bendavia, a mitochondria-targeted peptide, decreased oxidative stress and improved renal function and structure in CAS.
    1 context sentence
    Summary · context
    Pigs (seven each) were assigned to sham, left-circumflex CAS, renovascular HT, and CAS plus HT groups.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In pigs with coronary artery stenosis, Bendavia improved renal structure.

    In plain wordsIn pigs with a narrowed heart artery, Bendavia improved kidney structure.

    Peptide
    Elamipretide (SS-31)
    Outcome
    IncreaseRenal structure in CAS
    Study

    pign: not reported in source

    Swine with coronary artery stenosis (CAS)
    Outcome group
    Kidney function · Kidney and urinary
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Bendavia, a mitochondria-targeted peptide, decreased oxidative stress and improved renal function and structure in CAS.
    1 context sentence
    Summary · context
    Pigs (seven each) were assigned to sham, left-circumflex CAS, renovascular HT, and CAS plus HT groups.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 08:19 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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