Skip to content

Study · Animal study (in vivo) · quail · 2013

25 results

Kisspeptin-10 enhanced egg production in quails associated with the increase of triglyceride synthesis in liver.

Wu J, Fu W, Huang Y, Ni Y, Zhao R

Asian-Australasian Journal of Animal Sciences1 Aug 2013Cited by 9 (Europe PMC)

PMID25049888 (opens in a new tab)PMCIDPMC4093219 (opens in a new tab)DOI10.5713/ajas.2013.13014 (opens in a new tab)PepBankPUB-25049888
Read at sourcePubMedAsk about this study
Jump to 25 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study25

25 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In female quails, Kp-10 injections increased serum E2, and the increase was significant at the high dose.

    In plain wordsIn female quails, kisspeptin‑10 raised blood estradiol, significantly at the high dose.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseSerum estradiol
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    Serum E2 concentration was increased by Kp-10 injections, and reached statistical significance in H group.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In female quails, Kp-10 raised serum triglyceride by 46.7% at the low dose and 36.8% at the high dose, but not significantly.

    In plain wordsIn female quails, kisspeptin‑10 raised blood triglyceride, but the rise was not statistically significant.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeSerum triglyceride
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Lipids · Metabolic and weight
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Measurements

    Serum TG increase
    46.7%
    low dose
    Serum TG increase
    36.8%
    high dose

    Source sentences

    Summary
    Serum triglyceride (TG) concentrations were increased by 46.7% in L group and 36.8% in H group, respectively, but did not reach statistical significance
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In female quails, Kp-10 injections significantly increased liver triglyceride content in a dose-dependent manner.

    In plain wordsIn female quails, kisspeptin‑10 raised liver triglyceride, more at the higher dose.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseHepatic triglyceride content
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Liver fat and liver function · Liver
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    and TG contents in liver were significantly elevated by Kp-10 injections in a dose-dependent manner.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In female quails, Kp-10 at the high dose significantly decreased serum total cholesterol.

    In plain wordsIn female quails, the high kisspeptin‑10 dose lowered blood total cholesterol.

    Peptide
    Kisspeptin-10
    Outcome
    DecreaseSerum total cholesterol
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Lipids · Metabolic and weight
    Studied dose
    100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    Serum total cholesterol (Tch) concentrations significantly decreased in H group
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In female quails, Kp-10 at the high dose markedly increased liver total cholesterol content.

    In plain wordsIn female quails, the high kisspeptin‑10 dose raised liver cholesterol.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseHepatic total cholesterol content
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Liver fat and liver function · Liver
    Studied dose
    100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    while in H group the hepatic Tch content was markedly increased.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  6. 06AnimalAnimal study (in vivo)Efficacy outcome

    In female quails, Kp-10 did not alter serum non-esterified fatty acid.

    In plain wordsIn female quails, kisspeptin‑10 did not change blood fatty acids.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeSerum non-esterified fatty acid
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Lipids · Metabolic and weight
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    The level of non-esterified fatty acid (NEFA), apolipoprotein A1 and B (apoA1 and apoB) were not altered by Kp-10 injections.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  7. 07AnimalAnimal study (in vivo)Efficacy outcome

    In female quails, Kp-10 did not alter serum apoA1.

    In plain wordsIn female quails, kisspeptin‑10 did not change blood apolipoprotein A1.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeSerum apolipoprotein A1
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Lipids · Metabolic and weight
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    The level of non-esterified fatty acid (NEFA), apolipoprotein A1 and B (apoA1 and apoB) were not altered by Kp-10 injections.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  8. 08AnimalAnimal study (in vivo)Efficacy outcome

    In female quails, Kp-10 did not alter serum apoB.

    In plain wordsIn female quails, kisspeptin‑10 did not change blood apolipoprotein B.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeSerum apolipoprotein B
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Lipids · Metabolic and weight
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    The level of non-esterified fatty acid (NEFA), apolipoprotein A1 and B (apoA1 and apoB) were not altered by Kp-10 injections.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  9. 09AnimalAnimal study (in vivo)Mechanism

    In female quails, high-dose Kp-10, but not low-dose, up-regulated liver SREBP-1 mRNA versus control.

    In plain wordsIn female quails, the high kisspeptin‑10 dose raised liver SREBP-1 gene activity, the low dose did not.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseHepatic SREBP-1 mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    The genes expression of sterol regulatory element binding protein-1 (SREBP-1), fatty acid synthetase (FAS), apolipoprotein VLDL-II (apoVLDL-II), cholesterol 7α-hydroxylase (CYP7A1) and vitellogenin II (VTG-II) were significantly up-regulated by high but not low dosage of Kp-10 injection compared to the control group.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  10. 10AnimalAnimal study (in vivo)Mechanism

    In female quails, high-dose Kp-10, but not low-dose, up-regulated liver fatty acid synthetase mRNA versus control.

    In plain wordsIn female quails, the high kisspeptin‑10 dose raised liver fatty acid synthetase gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseHepatic FAS mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    The genes expression of sterol regulatory element binding protein-1 (SREBP-1), fatty acid synthetase (FAS), apolipoprotein VLDL-II (apoVLDL-II), cholesterol 7α-hydroxylase (CYP7A1) and vitellogenin II (VTG-II) were significantly up-regulated by high but not low dosage of Kp-10 injection compared to the control group.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  11. 11AnimalAnimal study (in vivo)Mechanism

    In female quails, high-dose Kp-10, but not low-dose, up-regulated liver apoVLDL-II mRNA versus control.

    In plain wordsIn female quails, the high kisspeptin‑10 dose raised liver apoVLDL-II gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseHepatic apoVLDL-II mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    The genes expression of sterol regulatory element binding protein-1 (SREBP-1), fatty acid synthetase (FAS), apolipoprotein VLDL-II (apoVLDL-II), cholesterol 7α-hydroxylase (CYP7A1) and vitellogenin II (VTG-II) were significantly up-regulated by high but not low dosage of Kp-10 injection compared to the control group.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  12. 12AnimalAnimal study (in vivo)Mechanism

    In female quails, high-dose Kp-10, but not low-dose, up-regulated liver CYP7A1 mRNA versus control.

    In plain wordsIn female quails, the high kisspeptin‑10 dose raised liver CYP7A1 gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseHepatic CYP7A1 mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    The genes expression of sterol regulatory element binding protein-1 (SREBP-1), fatty acid synthetase (FAS), apolipoprotein VLDL-II (apoVLDL-II), cholesterol 7α-hydroxylase (CYP7A1) and vitellogenin II (VTG-II) were significantly up-regulated by high but not low dosage of Kp-10 injection compared to the control group.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  13. 13AnimalAnimal study (in vivo)Mechanism

    In female quails, high-dose Kp-10, but not low-dose, up-regulated liver vitellogenin II mRNA versus control.

    In plain wordsIn female quails, the high kisspeptin‑10 dose raised liver vitellogenin II gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseHepatic vitellogenin II mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    The genes expression of sterol regulatory element binding protein-1 (SREBP-1), fatty acid synthetase (FAS), apolipoprotein VLDL-II (apoVLDL-II), cholesterol 7α-hydroxylase (CYP7A1) and vitellogenin II (VTG-II) were significantly up-regulated by high but not low dosage of Kp-10 injection compared to the control group.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  14. 14AnimalAnimal study (in vivo)Mechanism

    In female quails, Kp-10 did not affect liver SREBP-2 mRNA.

    In plain wordsIn female quails, kisspeptin‑10 did not change liver SREBP-2 gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeHepatic SREBP-2 mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    However, the expression of SREBP-2, acetyl-CoA carboxylase (ACCα), malic enzyme (ME), stearoyl-CoA (Δ9) desaturase 1 (SCD1), apolipoprotein A1 (apoA1), fatty acid binding protein 2 (FABP2), 3-hydroxyl-3-methyl glutaryl-coenzyme A reductases (HMGCR), estrogen receptor α, β (ERα and β) mRNA were not a…
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  15. 15AnimalAnimal study (in vivo)Mechanism

    In female quails, Kp-10 did not affect liver acetyl-CoA carboxylase alpha mRNA.

    In plain wordsIn female quails, kisspeptin‑10 did not change liver ACCα gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeHepatic ACCalpha mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    However, the expression of SREBP-2, acetyl-CoA carboxylase (ACCα), malic enzyme (ME), stearoyl-CoA (Δ9) desaturase 1 (SCD1), apolipoprotein A1 (apoA1), fatty acid binding protein 2 (FABP2), 3-hydroxyl-3-methyl glutaryl-coenzyme A reductases (HMGCR), estrogen receptor α, β (ERα and β) mRNA were not a…
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  16. 16AnimalAnimal study (in vivo)Mechanism

    In female quails, Kp-10 did not affect liver malic enzyme mRNA.

    In plain wordsIn female quails, kisspeptin‑10 did not change liver malic enzyme gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeHepatic malic enzyme mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    However, the expression of SREBP-2, acetyl-CoA carboxylase (ACCα), malic enzyme (ME), stearoyl-CoA (Δ9) desaturase 1 (SCD1), apolipoprotein A1 (apoA1), fatty acid binding protein 2 (FABP2), 3-hydroxyl-3-methyl glutaryl-coenzyme A reductases (HMGCR), estrogen receptor α, β (ERα and β) mRNA were not a…
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  17. 17AnimalAnimal study (in vivo)Mechanism

    In female quails, Kp-10 did not affect liver SCD1 mRNA.

    In plain wordsIn female quails, kisspeptin‑10 did not change liver SCD1 gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeHepatic SCD1 mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    However, the expression of SREBP-2, acetyl-CoA carboxylase (ACCα), malic enzyme (ME), stearoyl-CoA (Δ9) desaturase 1 (SCD1), apolipoprotein A1 (apoA1), fatty acid binding protein 2 (FABP2), 3-hydroxyl-3-methyl glutaryl-coenzyme A reductases (HMGCR), estrogen receptor α, β (ERα and β) mRNA were not a…
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  18. 18AnimalAnimal study (in vivo)Mechanism

    In female quails, Kp-10 did not affect liver apoA1 mRNA.

    In plain wordsIn female quails, kisspeptin‑10 did not change liver apoA1 gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeHepatic apoA1 mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    However, the expression of SREBP-2, acetyl-CoA carboxylase (ACCα), malic enzyme (ME), stearoyl-CoA (Δ9) desaturase 1 (SCD1), apolipoprotein A1 (apoA1), fatty acid binding protein 2 (FABP2), 3-hydroxyl-3-methyl glutaryl-coenzyme A reductases (HMGCR), estrogen receptor α, β (ERα and β) mRNA were not a…
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  19. 19AnimalAnimal study (in vivo)Mechanism

    In female quails, Kp-10 did not affect liver FABP2 mRNA.

    In plain wordsIn female quails, kisspeptin‑10 did not change liver FABP2 gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeHepatic FABP2 mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    However, the expression of SREBP-2, acetyl-CoA carboxylase (ACCα), malic enzyme (ME), stearoyl-CoA (Δ9) desaturase 1 (SCD1), apolipoprotein A1 (apoA1), fatty acid binding protein 2 (FABP2), 3-hydroxyl-3-methyl glutaryl-coenzyme A reductases (HMGCR), estrogen receptor α, β (ERα and β) mRNA were not a…
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  20. 20AnimalAnimal study (in vivo)Mechanism

    In female quails, Kp-10 did not affect liver HMGCR mRNA.

    In plain wordsIn female quails, kisspeptin‑10 did not change liver HMGCR gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeHepatic HMGCR mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    However, the expression of SREBP-2, acetyl-CoA carboxylase (ACCα), malic enzyme (ME), stearoyl-CoA (Δ9) desaturase 1 (SCD1), apolipoprotein A1 (apoA1), fatty acid binding protein 2 (FABP2), 3-hydroxyl-3-methyl glutaryl-coenzyme A reductases (HMGCR), estrogen receptor α, β (ERα and β) mRNA were not a…
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  21. 21AnimalAnimal study (in vivo)Mechanism

    In female quails, Kp-10 did not affect liver estrogen receptor alpha mRNA.

    In plain wordsIn female quails, kisspeptin‑10 did not change liver estrogen receptor alpha gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeHepatic estrogen receptor alpha mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    However, the expression of SREBP-2, acetyl-CoA carboxylase (ACCα), malic enzyme (ME), stearoyl-CoA (Δ9) desaturase 1 (SCD1), apolipoprotein A1 (apoA1), fatty acid binding protein 2 (FABP2), 3-hydroxyl-3-methyl glutaryl-coenzyme A reductases (HMGCR), estrogen receptor α, β (ERα and β) mRNA were not a…
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  22. 22AnimalAnimal study (in vivo)Mechanism

    In female quails, Kp-10 did not affect liver estrogen receptor beta mRNA.

    In plain wordsIn female quails, kisspeptin‑10 did not change liver estrogen receptor beta gene activity.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeHepatic estrogen receptor beta mRNA
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    However, the expression of SREBP-2, acetyl-CoA carboxylase (ACCα), malic enzyme (ME), stearoyl-CoA (Δ9) desaturase 1 (SCD1), apolipoprotein A1 (apoA1), fatty acid binding protein 2 (FABP2), 3-hydroxyl-3-methyl glutaryl-coenzyme A reductases (HMGCR), estrogen receptor α, β (ERα and β) mRNA were not a…
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  23. 23AnimalAnimal study (in vivo)Mechanism

    In female quails, high-dose Kp-10 significantly increased liver SREBP1 protein content.

    In plain wordsIn female quails, the high kisspeptin‑10 dose raised liver SREBP1 protein.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseHepatic SREBP1 protein
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    In line with hepatic mRNA abundance, hepatic SREBP1 protein content was significantly higher in H group.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  24. 24AnimalAnimal study (in vivo)Mechanism

    In female quails, high-dose Kp-10 significantly increased liver ERα protein content, although its mRNA did not change.

    In plain wordsIn female quails, the high kisspeptin‑10 dose raised liver estrogen receptor alpha protein.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseHepatic estrogen receptor alpha protein
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    Although the mRNA expression was not altered, the content of ERα protein in liver was also significantly increased in H group.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.
  25. 25AnimalAnimal study (in vivo)Mechanism

    In female quails, Kp-10 did not change liver SREBP-2 protein content.

    In plain wordsIn female quails, kisspeptin‑10 did not change liver SREBP-2 protein.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeHepatic SREBP-2 protein
    Study

    quailn = 75

    Female quails
    Comparator
    Control
    Outcome group
    Gene expression · Liver
    Studied dose
    10 nmol and 100 nmol · intraperitoneal · 3 weeksAs given in this study (quail).

    Source sentences

    Summary
    However, SREBP-2 protein content in liver was not changed by Kp-10 treatment.
    1 context sentence
    Summary · context
    75 female quails (22 d of age) were allocated to three groups randomly, and subjected to 0 (control, Con), 10 nmol (low dosage, L) and 100 nmol (high dosage, H) Kp-10 injections via i.p. once daily for three weeks, respectively.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.