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Study · In vitro (cells) · 2011

4 results

Activation of Neuropeptide FF Receptors by Kisspeptin Receptor Ligands.

Oishi S, Misu R, Tomita K, Setsuda S, Masuda R, Ohno H, Naniwa Y, Ieda N, Inoue N, Ohkura S, Uenoyama Y, Tsukamura H and 4 more

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Maeda K, Hirasawa A, Tsujimoto G, Fujii N

ACS medicinal chemistry letters25 Oct 2010Cited by 74 (Europe PMC)

PMID24900254 (opens in a new tab)PMCIDPMC4018085 (opens in a new tab)DOI10.1021/ml1002053 (opens in a new tab)PepBankPUB-24900254
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    Kisspeptin‑10 bound potently to neuropeptide FF receptor 1 (NPFFR1).

    In plain wordsIn lab tests, kisspeptin‑10 bound strongly to the neuropeptide FF receptor 1.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableBinding to neuropeptide FF receptor 1 (NPFFR1)
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Kisspeptin-10 exhibited potent binding and activation of neuropeptide FF receptors (NPFFR1 and NPFFR2).
    1 context sentence
    Summary · context
    In the present study, the selectivity profiles of GPR54 agonist peptides were investigated for several GPCRs, including RFamide receptors.
  2. 02LabIn vitro (cells)Activity measurement

    Kisspeptin‑10 bound potently to neuropeptide FF receptor 2 (NPFFR2).

    In plain wordsIn lab tests, kisspeptin‑10 bound strongly to the neuropeptide FF receptor 2.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableBinding to neuropeptide FF receptor 2 (NPFFR2)
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Kisspeptin-10 exhibited potent binding and activation of neuropeptide FF receptors (NPFFR1 and NPFFR2).
    1 context sentence
    Summary · context
    In the present study, the selectivity profiles of GPR54 agonist peptides were investigated for several GPCRs, including RFamide receptors.
  3. 03LabIn vitro (cells)Activity measurement

    Kisspeptin‑10 potently activated neuropeptide FF receptor 1 (NPFFR1).

    In plain wordsIn lab tests, kisspeptin‑10 strongly switched on the neuropeptide FF receptor 1.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableActivation of neuropeptide FF receptor 1 (NPFFR1)
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Kisspeptin-10 exhibited potent binding and activation of neuropeptide FF receptors (NPFFR1 and NPFFR2).
    1 context sentence
    Summary · context
    In the present study, the selectivity profiles of GPR54 agonist peptides were investigated for several GPCRs, including RFamide receptors.
  4. 04LabIn vitro (cells)Activity measurement

    Kisspeptin‑10 potently activated neuropeptide FF receptor 2 (NPFFR2).

    In plain wordsIn lab tests, kisspeptin‑10 strongly switched on the neuropeptide FF receptor 2.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableActivation of neuropeptide FF receptor 2 (NPFFR2)
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Kisspeptin-10 exhibited potent binding and activation of neuropeptide FF receptors (NPFFR1 and NPFFR2).
    1 context sentence
    Summary · context
    In the present study, the selectivity profiles of GPR54 agonist peptides were investigated for several GPCRs, including RFamide receptors.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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