Anserine and carnosine supplementation in the elderly: Effects on cognitive functioning and physical capacity.

Szcześniak D, Budzeń S, Kopeć W, Rymaszewska J

Archives of gerontology and geriatrics2 May 2014Cited by 82 (Europe PMC)

PMID24880197DOI10.1016/j.archger.2014.04.008PepBankPUB-24880197

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone6

In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking L-carnosine.

01HumanNot a test of L-carnosine aloneNon-randomized trialEfficacy outcome
In older adults, anserine-carnosine chicken extract significantly decreased BMI versus placebo.
In plain wordsIn older adults, anserine-carnosine chicken extract lowered BMI compared with placebo.
Peptide
L-carnosine
Outcome
DecreaseBMI
Study
n = 51
Comparator
placebo
Outcome group
Body weight · Metabolic and weight
Source sentences
Summary
After supplementation Body Mass Index (BMI) decreased significantly (p<0.05) in the CRC group performance comparing the placebo group.
4 context sentences(design, population, supporting numbers)
Summary · context
The fifty-six subjects (65+) were allocated to the CRC group or placebo group at a 1:1 ratio.
Summary · context
The double-blind procedure was used.
Summary · context
Data were collected at the baseline and after 13-weeks of supplementation.
Summary · context
Chicken meat extract (CME) containing 40% of CRC components (2:1 ratio of anserine to carnosine) was administered 2.5 g per day which allowed to rich the level of 1g CRC in dipeptides supplement.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-2488019701
02HumanNot a test of L-carnosine aloneNon-randomized trialEfficacy outcome
In older adults, anserine-carnosine chicken extract significantly increased scores in two of six Senior Fitness Tests versus placebo.
In plain wordsIn older adults, anserine-carnosine chicken extract improved two fitness test scores compared with placebo.
Peptide
L-carnosine
Outcome
IncreaseSenior Fitness Test scores
Study
n = 51
Comparator
placebo
Outcome group
Exercise and physical function · Musculoskeletal
Source sentences
Summary
In two of six Senior Fitness Test the scores increased significantly (p<0.05) in CRC group comparing to the placebo group.
4 context sentences(design, population, supporting numbers)
Summary · context
The fifty-six subjects (65+) were allocated to the CRC group or placebo group at a 1:1 ratio.
Summary · context
The double-blind procedure was used.
Summary · context
Data were collected at the baseline and after 13-weeks of supplementation.
Summary · context
Chicken meat extract (CME) containing 40% of CRC components (2:1 ratio of anserine to carnosine) was administered 2.5 g per day which allowed to rich the level of 1g CRC in dipeptides supplement.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-2488019702
03HumanNot a test of L-carnosine aloneNon-randomized trialEfficacy outcome
In older adults receiving anserine-carnosine chicken extract, perceived exertion differed significantly from baseline, with direction unstated.
In plain wordsIn older adults receiving anserine-carnosine chicken extract, perceived exertion changed from baseline, but the abstract gives no direction.
Peptide
L-carnosine
Outcome
Direction not reportedPerceived exertion
Study
n: not reported in source
Comparator
baseline
Outcome group
Exercise and physical function · Musculoskeletal
Source sentences
Summary
The perceived exertion differed significantly (p<0.05) at the baseline and after follow up at the CRC group.
4 context sentences(design, population, supporting numbers)
Summary · context
The fifty-six subjects (65+) were allocated to the CRC group or placebo group at a 1:1 ratio.
Summary · context
The double-blind procedure was used.
Summary · context
Data were collected at the baseline and after 13-weeks of supplementation.
Summary · context
Chicken meat extract (CME) containing 40% of CRC components (2:1 ratio of anserine to carnosine) was administered 2.5 g per day which allowed to rich the level of 1g CRC in dipeptides supplement.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-2488019703
04HumanNot a test of L-carnosine aloneNon-randomized trialEfficacy outcome
In older adults, construction/copying subscores significantly increased only in the anserine-carnosine chicken extract group.
In plain wordsIn older adults, construction and copying scores increased from baseline only with anserine-carnosine chicken extract.
Peptide
L-carnosine
Outcome
IncreaseConstruction/copying subscore
Study
n: not reported in source
Comparator
baseline
Outcome group
Cognition and memory · Nervous system and cognition
Source sentences
Summary
The mean values of the Short Test of Mental Status (STMS) scores showed the significant (p<0.04) increase only in CRC group, in the subscores of construction/copying, abstraction and recall.
4 context sentences(design, population, supporting numbers)
Summary · context
The fifty-six subjects (65+) were allocated to the CRC group or placebo group at a 1:1 ratio.
Summary · context
The double-blind procedure was used.
Summary · context
Data were collected at the baseline and after 13-weeks of supplementation.
Summary · context
Chicken meat extract (CME) containing 40% of CRC components (2:1 ratio of anserine to carnosine) was administered 2.5 g per day which allowed to rich the level of 1g CRC in dipeptides supplement.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-2488019705
05HumanNot a test of L-carnosine aloneNon-randomized trialEfficacy outcome
In older adults, abstraction subscores significantly increased only in the anserine-carnosine chicken extract group.
In plain wordsIn older adults, abstraction scores increased from baseline only with anserine-carnosine chicken extract.
Peptide
L-carnosine
Outcome
IncreaseAbstraction subscore
Study
n: not reported in source
Comparator
baseline
Outcome group
Cognition and memory · Nervous system and cognition
Source sentences
Summary
The mean values of the Short Test of Mental Status (STMS) scores showed the significant (p<0.04) increase only in CRC group, in the subscores of construction/copying, abstraction and recall.
4 context sentences(design, population, supporting numbers)
Summary · context
The fifty-six subjects (65+) were allocated to the CRC group or placebo group at a 1:1 ratio.
Summary · context
The double-blind procedure was used.
Summary · context
Data were collected at the baseline and after 13-weeks of supplementation.
Summary · context
Chicken meat extract (CME) containing 40% of CRC components (2:1 ratio of anserine to carnosine) was administered 2.5 g per day which allowed to rich the level of 1g CRC in dipeptides supplement.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-2488019706
06HumanNot a test of L-carnosine aloneNon-randomized trialEfficacy outcome
In older adults, recall subscores significantly increased only in the anserine-carnosine chicken extract group.
In plain wordsIn older adults, recall scores increased from baseline only with anserine-carnosine chicken extract.
Peptide
L-carnosine
Outcome
IncreaseRecall subscore
Study
n: not reported in source
Comparator
baseline
Outcome group
Cognition and memory · Nervous system and cognition
Source sentences
Summary
The mean values of the Short Test of Mental Status (STMS) scores showed the significant (p<0.04) increase only in CRC group, in the subscores of construction/copying, abstraction and recall.
4 context sentences(design, population, supporting numbers)
Summary · context
The fifty-six subjects (65+) were allocated to the CRC group or placebo group at a 1:1 ratio.
Summary · context
The double-blind procedure was used.
Summary · context
Data were collected at the baseline and after 13-weeks of supplementation.
Summary · context
Chicken meat extract (CME) containing 40% of CRC components (2:1 ratio of anserine to carnosine) was administered 2.5 g per day which allowed to rich the level of 1g CRC in dipeptides supplement.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-2488019707

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
27 Oct 2026, 18:20 UTC
Study results updated
Version 1
27 Oct 2026, 16:32 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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