Skip to content

Study · Observational study · 2014

9 results

Surgical and anesthetic considerations in histrelin capsule implantation for the treatment of precocious puberty.

Davis JS, Alkhoury F, Burnweit C

Journal of pediatric surgery22 Feb 2014Cited by 14 (Europe PMC)

PMID24851775 (opens in a new tab)DOI10.1016/j.jpedsurg.2014.02.067 (opens in a new tab)PepBankPUB-24851775
Publisher pagePubMedAsk about this study
Jump to 9 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study9

9 results from studies that gave the peptide. 9 results from people.

  1. 01HumanObservational studySafety outcome

    In histrelin implant procedures for precocious puberty, procedural difficulties occurred in 18 cases (16%).

    In plain wordsIn histrelin implant procedures for precocious puberty, difficulties occurred in 18 cases (16%).

    Peptide
    Histrelin
    Outcome
    Not applicableProcedural difficulties
    Study

    n: not reported in source

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated

    Measurements

    Procedural difficulties
    18 cases
    implant procedures
    Procedural difficulties
    16%
    implant procedures

    Source sentences

    Summary
    Procedural difficulties (n=18, 16%) included implant fracture during removal (n=16/58 removals, 28%).
    1 context sentence
    Summary · context
    All cases from one surgeon at a tertiary pediatric hospital were reviewed for patient age, anesthetic type, technical difficulties, and complications.
  2. 02HumanObservational studySafety outcome

    During histrelin implant removal, fracture occurred in 16 of 58 removals (28%).

    In plain wordsHistrelin implants fractured during 16 of 58 removals (28%).

    Peptide
    Histrelin
    Outcome
    Not applicableImplant fracture during removal
    Study

    n: not reported in source

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated

    Measurements

    Implant fractures during removal
    16 removals
    of 58 removals
    Implant fractures during removal
    28%
    removals

    Source sentences

    Summary
    Procedural difficulties (n=18, 16%) included implant fracture during removal (n=16/58 removals, 28%).
    1 context sentence
    Summary · context
    All cases from one surgeon at a tertiary pediatric hospital were reviewed for patient age, anesthetic type, technical difficulties, and complications.
  3. 03HumanObservational studySafety outcome

    In histrelin procedures for precocious puberty, fracture never occurred during implantation.

    In plain wordsHistrelin implants never fractured during implantation in this study.

    Peptide
    Histrelin
    Outcome
    Not applicableImplant fracture during implantation
    Study

    n: not reported in source

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Fracture never occurred during implantation.
    1 context sentence
    Summary · context
    All cases from one surgeon at a tertiary pediatric hospital were reviewed for patient age, anesthetic type, technical difficulties, and complications.
  4. 04HumanObservational studySafety outcome

    After histrelin procedures, 3 children (3%) suffered complications.

    In plain wordsAfter histrelin procedures, 3 children (3%) had complications.

    Peptide
    Histrelin
    Outcome
    Not applicableComplications
    Study

    n: not reported in source

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated

    Measurements

    Children with complications
    3 children
    histrelin procedures
    Children with complications
    3%
    histrelin procedures

    Source sentences

    Summary
    Three children (3%) suffered complications.
    1 context sentence
    Summary · context
    All cases from one surgeon at a tertiary pediatric hospital were reviewed for patient age, anesthetic type, technical difficulties, and complications.
  5. 05HumanObservational studySafety outcome

    After histrelin procedures, one infection required antibiotics.

    In plain wordsAfter histrelin procedures, one infection required antibiotics.

    Peptide
    Histrelin
    Outcome
    Not applicableInfection
    Study

    n: not reported in source

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated

    Measurements

    Infections treated with antibiotics
    1 infection
    histrelin procedures

    Source sentences

    Summary
    One infection was treated with antibiotics, and two implants were removed for systemic allergic reaction.
    1 context sentence
    Summary · context
    All cases from one surgeon at a tertiary pediatric hospital were reviewed for patient age, anesthetic type, technical difficulties, and complications.
  6. 06HumanObservational studySafety outcome

    Two histrelin implants were removed because of systemic allergic reactions.

    In plain wordsTwo histrelin implants required removal because of systemic allergic reactions.

    Peptide
    Histrelin
    Outcome
    Not applicableSystemic allergic reaction requiring removal
    Study

    n: not reported in source

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated

    Measurements

    Implants removed for systemic allergic reaction
    2 implants
    histrelin procedures

    Source sentences

    Summary
    One infection was treated with antibiotics, and two implants were removed for systemic allergic reaction.
    1 context sentence
    Summary · context
    All cases from one surgeon at a tertiary pediatric hospital were reviewed for patient age, anesthetic type, technical difficulties, and complications.
  7. 07HumanObservational studySafety outcome

    After histrelin procedures, 6 children (5%) had unscheduled postoperative checks.

    In plain wordsAfter histrelin procedures, 6 children (5%) needed unscheduled checks.

    Peptide
    Histrelin
    Outcome
    Not applicableUnscheduled postoperative checks
    Study

    n: not reported in source

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated

    Measurements

    Children with unscheduled post-operative checks
    6 children
    histrelin procedures
    Children with unscheduled post-operative checks
    5%
    histrelin procedures

    Source sentences

    Summary
    Six children (5%) had unscheduled post-operative checks for pain (n=3, 3%), allergy to elastic dressing (n=2, 2%), or rash (n=1, 1%).
    1 context sentence
    Summary · context
    All cases from one surgeon at a tertiary pediatric hospital were reviewed for patient age, anesthetic type, technical difficulties, and complications.
  8. 08HumanObservational studySafety outcome

    After histrelin procedures, 3 children (3%) had unscheduled postoperative checks for pain.

    In plain wordsAfter histrelin procedures, 3 children (3%) needed unscheduled checks for pain.

    Peptide
    Histrelin
    Outcome
    Not applicablePain requiring postoperative check
    Study

    n: not reported in source

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated

    Measurements

    Unscheduled checks for pain
    3 children
    histrelin procedures
    Unscheduled checks for pain
    3%
    histrelin procedures

    Source sentences

    Summary
    Six children (5%) had unscheduled post-operative checks for pain (n=3, 3%), allergy to elastic dressing (n=2, 2%), or rash (n=1, 1%).
    1 context sentence
    Summary · context
    All cases from one surgeon at a tertiary pediatric hospital were reviewed for patient age, anesthetic type, technical difficulties, and complications.
  9. 09HumanObservational studySafety outcome

    After histrelin procedures, 1 child (1%) had an unscheduled postoperative check for rash.

    In plain wordsAfter histrelin procedures, 1 child (1%) needed an unscheduled check for rash.

    Peptide
    Histrelin
    Outcome
    Not applicableRash requiring postoperative check
    Study

    n: not reported in source

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated

    Measurements

    Unscheduled checks for rash
    1 child
    histrelin procedures
    Unscheduled checks for rash
    1%
    histrelin procedures

    Source sentences

    Summary
    Six children (5%) had unscheduled post-operative checks for pain (n=3, 3%), allergy to elastic dressing (n=2, 2%), or rash (n=1, 1%).
    1 context sentence
    Summary · context
    All cases from one surgeon at a tertiary pediatric hospital were reviewed for patient age, anesthetic type, technical difficulties, and complications.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.