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Study · Not a test of the peptide alone · 2014

2 results

Re-activated adult epicardial progenitor cells are a heterogeneous population molecularly distinct from their embryonic counterparts.

Bollini S, Vieira JM, Howard S, Dubè KN, Balmer GM, Smart N, Riley PR

Stem cells and development8 May 2014Cited by 73 (Europe PMC)

PMID24702282 (opens in a new tab)DOI10.1089/scd.2014.0019 (opens in a new tab)PepBankPUB-24702282
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 01AnimalNot a test of Thymosin beta-4 (human) aloneAnimal study (in vivo)Mechanism

    In Tβ4-primed mice after myocardial infarction, activated adult WT1-positive epicardium-derived cells were highly heterogeneous and expressed cardiac progenitor and mesenchymal stem markers.

    In plain wordsIn mice primed with Tβ4 and then given a heart attack, the activated heart-surface cells were highly varied.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableHeterogeneity of adult epicardium-derived cells
    Study

    mousen: not reported in source

    Wt1(GFPCre/+) mice primed with Tβ4 with myocardial infarction
    Outcome group
    Heart function · Cardiovascular

    Source sentences

    Summary
    Adult WT1(+) GFP(+) EPDCs were highly heterogeneous, expressing cardiac progenitor and mesenchymal stem markers.
    1 context sentence
    Summary · context
    Wt1(GFPCre/+) mice were primed with Tβ4 and MI induced by ligation of the left anterior descending coronary artery.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  2. 02AnimalNot a test of Thymosin beta-4 (human) aloneAnimal study (in vivo)Mechanism

    In Tβ4-primed mice after myocardial infarction, adult epicardium-derived cell subpopulations had a molecular phenotype distinct from embryonic epicardial cells at E12.5.

    In plain wordsIn mice primed with Tβ4 and then given a heart attack, adult heart-surface cells differed in makeup from embryonic ones.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableAdult versus embryonic epicardium-derived cell phenotype
    Study

    mousen: not reported in source

    Wt1(GFPCre/+) mice primed with Tβ4 with myocardial infarction
    Comparator
    Embryonic epicardial cells at E12.5
    Outcome group
    Heart function · Cardiovascular

    Source sentences

    Summary
    Based on the expression of stem cell antigen-1 (Sca-1), CD44, and CD90, we identified different subpopulations of EPDCs of varying cardiovascular potential, according to marker gene profiles, with a molecular phenotype distinct from the source embryonic epicardial cells at E12.5.
    1 context sentence
    Summary · context
    Wt1(GFPCre/+) mice were primed with Tβ4 and MI induced by ligation of the left anterior descending coronary artery.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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