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Study · Animal study (in vivo) · rhesus monkey · 2014

3 results

Primate HPT axis response to the peripheral kisspeptin challenge under different time periods of food restriction in monkeys.

Wahab F, Atika B, Huma T, Shahab M

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme5 Feb 2014Cited by 3 (Europe PMC)

PMID24500987 (opens in a new tab)DOI10.1055/s-0033-1363263 (opens in a new tab)PepBankPUB-24500987
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In adult male rhesus monkeys, kisspeptin‑10 highly stimulated testosterone secretion in fasting and fed conditions.

    In plain wordsIn male monkeys, kisspeptin‑10 strongly raised testosterone, whether the animals were fasted or fed.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseTestosterone secretion after kisspeptin-10
    Study

    rhesus monkeyn = 5

    Intact sexually mature male rhesus monkeys
    Comparator
    Vehicle
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    50 μg · intravenous bolusAs given in this study (rhesus monkey).

    Source sentences

    Summary
    KP10 injection highly stimulated testosterone secretion in all conditions.
    1 context sentence
    Summary · context
    Intravenous boli of vehicle (1 ml) and human kisspeptin-10 (KP10; 50 μg) were given to 5 intact sexually mature male rhesus monkeys in both fasting (12-, 18-, 24-h) and ad libitum feeding conditions.

Studies that did not test the peptide alone2

In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Kisspeptin-10.

  1. 02AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Efficacy outcome

    In adult male rhesus monkeys, 18-h and 24-h fasting reduced the mean testosterone response to kisspeptin‑10 compared with 12-h fasting and feeding.

    In plain wordsIn male monkeys, fasting for 18 or 24 hours weakened the testosterone rise after kisspeptin‑10 compared with shorter fasting or feeding.

    Peptide
    Kisspeptin-10
    Outcome
    DecreaseTestosterone response to kisspeptin-10 after 18 and 24 hours of fasting
    Study

    rhesus monkeyn = 5

    Intact sexually mature male rhesus monkeys
    Comparator
    12-h fasted and fed monkeys
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    However, mean testosterone concentrations in 3-h post-KP10 injection period were significantly (p<0.01) decreased in 18- and 24-h fasted monkeys when compared to 12-h fasted and fed monkeys.
    1 context sentence
    Summary · context
    Intravenous boli of vehicle (1 ml) and human kisspeptin-10 (KP10; 50 μg) were given to 5 intact sexually mature male rhesus monkeys in both fasting (12-, 18-, 24-h) and ad libitum feeding conditions.

    In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.

  2. 03AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Efficacy outcome

    In adult male rhesus monkeys, 18-h and 24-h fasting delayed the time to the first significant testosterone increase after kisspeptin‑10.

    In plain wordsIn male monkeys, fasting for 18 or 24 hours delayed the first testosterone rise after kisspeptin‑10.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseTime to first testosterone increase after kisspeptin-10 with 18 and 24 hours of fasting
    Study

    rhesus monkeyn = 5

    Intact sexually mature male rhesus monkeys
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    Moreover, 18- and 24-h fasting conditions also significantly (p<0.05) delayed the duration to the first significant increase in T levels after KP10 injection.
    1 context sentence
    Summary · context
    Intravenous boli of vehicle (1 ml) and human kisspeptin-10 (KP10; 50 μg) were given to 5 intact sexually mature male rhesus monkeys in both fasting (12-, 18-, 24-h) and ad libitum feeding conditions.

    In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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