In mice with mammary carcinoma, intravenous desmopressin markedly decreased vascularization of growing subcutaneous tumors.
In plain wordsIn mice with mammary cancer, desmopressin reduced blood vessel formation in growing tumors.
- Peptide
- Desmopressin
- Outcome
- DecreaseTumor vascularization
- Study
mousen: not reported in source
F3II mammary carcinoma in syngeneic Balb/c mice- Outcome group
- Tumor growth · Cancer
- Studied dose
- 2 μg/kg · intravenousAs given in this study (mouse).
Source sentences
Intravenous administration of the compound (2 μg/kg) markedly decreased vascularization of growing subcutaneous tumors, as well as inhibited the early angiogenic response around intradermal inoculation sites.
1 context sentence(design, population, supporting numbers)
Here, we explored the effects of DDAVP on tumor angiogenesis using the aggressive F3II mammary carcinoma in syngeneic Balb/c mice.