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Study · Ex vivo tissue · frog (rana esculenta) · 2013

3 results

Kisspeptin receptor, GPR54, as a candidate for the regulation of testicular activity in the frog Rana esculenta.

Chianese R, Ciaramella V, Fasano S, Pierantoni R, Meccariello R

Biology of reproduction28 Mar 2013Cited by 33 (Europe PMC)

PMID23365413 (opens in a new tab)DOI10.1095/biolreprod.112.103515 (opens in a new tab)PepBankPUB-23365413
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueMechanism

    In frog testis in February, kisspeptin‑10 induced testicular GPR54 expression in a dose-dependent manner.

    In plain wordsIn frog testis tissue, kisspeptin‑10 raised the amount of its own receptor, GPR54, depending on dose.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseTesticular GPR54 expression in February
    Study

    frog (Rana esculenta)n: not reported in source

    Testis
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Furthermore, in February, kisspeptin-10 (Kp-10) induced the testicular expression of both GPR54 and estrogen receptor alpha (ERalpha) in a dose-dependent manner
  2. 02LabEx vivo tissueMechanism

    In frog testis in February, kisspeptin‑10 induced testicular estrogen receptor alpha expression in a dose-dependent manner.

    In plain wordsIn frog testis tissue, kisspeptin‑10 raised the amount of estrogen receptor alpha, depending on dose.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseTesticular ERalpha expression in February
    Study

    frog (Rana esculenta)n: not reported in source

    Testis
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Furthermore, in February, kisspeptin-10 (Kp-10) induced the testicular expression of both GPR54 and estrogen receptor alpha (ERalpha) in a dose-dependent manner.
  3. 03LabEx vivo tissueMechanism

    In frog testis in March, kisspeptin‑10 had a biphasic effect on ERalpha expression, inhibitory at 1 h and stimulatory at 4 h.

    In plain wordsIn frog testis tissue, kisspeptin‑10 first lowered and later raised estrogen receptor alpha levels.

    Peptide
    Kisspeptin-10
    Outcome
    MixedTesticular ERalpha expression in March over time
    Study

    frog (Rana esculenta)n: not reported in source

    Testis
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · 1 h and 4 hAs given in this study (frog (Rana esculenta)).

    Source sentences

    Summary
    Conversely, in March, Kp-10 had a biphasic effect on the expression of ERalpha, being inhibitory at short (1 h) and stimulatory at longer (4 h) incubation time.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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