Study · Animal study (in vivo) · rat · 2013
5 resultsKim JY, Lee SK, Jo KJ, Song DY, Lim DM, Park KY, Bonewald LF, Kim BJ
Life sciences25 Jan 2013Cited by 113 (Europe PMC)
The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)
Text rights: Publisher copyright. Results still quote short attributed sentences.
5 results from studies that gave the peptide. No result from this study comes from people.
In type 2 diabetic OLETF rats, exendin‑4 reduced serum sclerostin.
In plain wordsIn rats with diabetes, exendin‑4 reduced blood sclerostin.
ratn: not reported in source
Type 2 diabetic OLETF ratsSource sentences
Exendin-4 reduced serum levels of sclerostin, increased serum levels of osteocalcin, and increased femoral BMD in type 2 diabetic OLETF rats.
In type 2 diabetic OLETF rats, exendin‑4 increased serum osteocalcin.
In plain wordsIn rats with diabetes, exendin‑4 increased blood osteocalcin.
ratn: not reported in source
Type 2 diabetic OLETF ratsSource sentences
Exendin-4 reduced serum levels of sclerostin, increased serum levels of osteocalcin, and increased femoral BMD in type 2 diabetic OLETF rats.
In type 2 diabetic OLETF rats, exendin‑4 increased femoral bone mineral density.
In plain wordsIn rats with diabetes, exendin‑4 increased thigh bone mineral density.
ratn: not reported in source
Type 2 diabetic OLETF ratsSource sentences
Exendin-4 reduced serum levels of sclerostin, increased serum levels of osteocalcin, and increased femoral BMD in type 2 diabetic OLETF rats.
In MLO-Y4 cells, exendin‑4 reduced SOST mRNA expression under normal or high-glucose conditions.
In plain wordsIn cells, exendin‑4 reduced SOST gene expression under normal or high-glucose conditions.
n: not reported in source
MLO-Y4 osteocyte-like cellsSource sentences
Exendin-4 reduced the mRNA expression and protein production of SOST/sclerostin under normal or high-glucose conditions in MLO-Y4 cells.
In MLO-Y4 cells, exendin‑4 reduced sclerostin protein production under normal or high-glucose conditions.
In plain wordsIn cells, exendin‑4 reduced sclerostin protein production under normal or high-glucose conditions.
n: not reported in source
MLO-Y4 osteocyte-like cellsSource sentences
Exendin-4 reduced the mRNA expression and protein production of SOST/sclerostin under normal or high-glucose conditions in MLO-Y4 cells.
AI wrote and checked these results. AI can make mistakes, so check important results against the source.
PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.
Version 2Current
22 Oct 2026, 02:26 UTC
Study results updated
Version 1
21 Oct 2026, 18:59 UTC
First added · source update from Europe PMC
Terms as the source lists them.
PepBank is a research reference. Talk to a doctor before you use any peptide.
In PepBank now:147 peptides, 6 blends and 13 other compounds97,577 study results from 17,383 studies8,473 clinical trialsUpdated