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Study · Animal study (in vivo) · horse · 2012

2 results

Doping control analysis of TB-500, a synthetic version of an active region of thymosin β₄, in equine urine and plasma by liquid chromatography-mass spectrometry.

Ho EN, Kwok WH, Lau MY, Wong AS, Wan TS, Lam KK, Schiff PJ, Stewart BD

Journal of chromatography. A23 Sept 2012Cited by 33 (Europe PMC)

PMID23084823 (opens in a new tab)DOI10.1016/j.chroma.2012.09.043 (opens in a new tab)PepBankPUB-23084823
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Pharmacokinetics

    In horses given a single dose of TB‑500 (10 mg of N-acetylated LKKTETQ), the method confirmed N-acetylated LKKTETQ and its metabolites in urine and plasma.

    In plain wordsIn horses given one dose of TB‑500, the test found the peptide and its breakdown products in urine and plasma.

    Peptide
    TB-500
    Outcome
    Not applicableDetection of N-acetylated LKKTETQ and metabolites after dosing
    Study

    horsen: not reported in source

    horses given a single dose of TB-500
    Outcome group
    Pharmacokinetics · Pharmacology
    Studied dose
    single dose containing 10 mg N-acetylated LKKTETQ · single doseAs given in this study (horse).

    Source sentences

    Summary
    This method was successful in confirming the presence of N-acetylated LKKTETQ and its metabolites in equine urine and plasma collected from horses administered with a single dose of TB-500 (containing 10mg of N-acetylated LKKTETQ).
    1 context sentence
    Title · context
    Doping control analysis of TB-500, a synthetic version of an active region of thymosin β₄, in equine urine and plasma by liquid chromatography-mass spectrometry.

Studies that did not test the peptide alone1

In this study, TB-500 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking TB-500.

  1. 02LabNot a test of TB-500 aloneIn vitro (cell-free)Other

    A mass spectrometry method detected and confirmed N-acetylated LKKTETQ at 0.02 ng/mL in equine plasma and 0.01 ng/mL in equine urine.

    In plain wordsIn horse samples, a lab test could find the TB‑500 peptide at very low levels in plasma and urine.

    Peptide
    TB-500
    Outcome
    Not applicableDetection limit of N-acetylated LKKTETQ
    Study

    horsen: not reported in source

    equine plasma and urine
    Outcome group
    Pharmacokinetics · Pharmacology

    Measurements

    Detection limit
    0.02 ng/mL
    equine plasma
    Detection limit
    0.01 ng/mL
    equine urine

    Source sentences

    Summary
    The peptide N-acetylated LKKTETQ could be detected and confirmed at 0.02 ng/mL in equine plasma and 0.01 ng/mL in equine urine.
    1 context sentence
    Title · context
    Doping control analysis of TB-500, a synthetic version of an active region of thymosin β₄, in equine urine and plasma by liquid chromatography-mass spectrometry.

    In this study, TB-500 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking TB-500.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 4Current

    12 Oct 2026, 18:17 UTC

    Study data updated · source update from Europe PMC

  2. Version 3

    9 Oct 2026, 18:17 UTC

    Study results updated

  3. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  4. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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