Skip to content

Study · Randomized controlled trial · n = 60 · 2012

3 results

[Efficacy of reflexology in the combination with neuroprotective treatment in hemiparetic form of children cerebral palsy].

Ukhanova TA, Gorbunov FE

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova1 Jan 2012

PMID23011423 (opens in a new tab)PepBankPUB-23011423
Publisher pageAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In children with hemiparetic cerebral palsy, some ambulation skills developed in 97% with added Cortexin and in 90% with reflexology alone.

    In plain wordsIn children with cerebral palsy, some walking skills developed in 97% with added Cortexin and in 90% with reflexology alone.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    Direction not reportedAmbulation skill development
    Study

    n = 60

    Comparator
    Microcurrent reflexology without Cortexin
    Outcome group
    Exercise and physical function · Nervous system and cognition
    Studied dose
    10 mg · intramuscular · Two courses, 10 injections per courseAs given in this study (human).

    Measurements

    Ambulation skills
    97%
    Cortexin plus reflexology
    Ambulation skills
    90%
    Reflexology alone

    Source sentences

    Summary
    This treatment showed the beneficial effects: 29 patients of the first group (97%) and 27 patients of the second group (90%) developed some ambulation skills.
    7 context sentences
    Summary · context
    Sixty patients with the diagnosis of cerebral palsy with hemiparesis at the age from 2 to 7 years were treated.
    Summary · context
    All 60 patients had conventional treatment including massage and exercise therapy.
    Summary · context
    Patients were divided into 2 randomized groups.
    Summary · context
    The patients of the first group were given 3 sets of microcurrent reflexology sessions and 2 courses of treatment with cortexin.
    Summary · context
    Patients of the second group were given reflexology treatments only.
    Summary · context
    Cortexin was introduced intramuscularly in dosage 10 mg.
    Summary · context
    The treatment included 10 injections.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In children with hemiparetic cerebral palsy, upper-limb manipulative activity improved in 37% with added Cortexin versus 17% with reflexology alone.

    In plain wordsIn children with cerebral palsy, arm manipulation improved in 37% with added Cortexin versus 17% with reflexology alone.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    IncreaseManipulative activity of paralyzed upper extremities
    Study

    n = 60

    Comparator
    Microcurrent reflexology without Cortexin
    Outcome group
    Exercise and physical function · Nervous system and cognition
    Studied dose
    10 mg · intramuscular · Two courses, 10 injections per courseAs given in this study (human).

    Measurements

    Manipulative activity improvement
    37%
    Cortexin plus reflexology
    Manipulative activity improvement
    17%
    Reflexology alone
    Relative progress
    2.2 times
    Cortexin plus reflexology versus reflexology alone

    Source sentences

    Summary
    The progress in complicated manipulative activity of paralyzed upper extremities under microcurrent reflexology with cortexin was 2.2 times more visible in patients of the first group compared to the second one (11 patients (37%) versus 5 patients (17%), respectively).
    7 context sentences
    Summary · context
    Sixty patients with the diagnosis of cerebral palsy with hemiparesis at the age from 2 to 7 years were treated.
    Summary · context
    All 60 patients had conventional treatment including massage and exercise therapy.
    Summary · context
    Patients were divided into 2 randomized groups.
    Summary · context
    The patients of the first group were given 3 sets of microcurrent reflexology sessions and 2 courses of treatment with cortexin.
    Summary · context
    Patients of the second group were given reflexology treatments only.
    Summary · context
    Cortexin was introduced intramuscularly in dosage 10 mg.
    Summary · context
    The treatment included 10 injections.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In children with hemiparetic cerebral palsy, positive EEG changes occurred in 71% with added Cortexin versus 53% with reflexology alone.

    In plain wordsIn children with cerebral palsy, brain electrical activity improved in 71% with added Cortexin versus 53% with reflexology alone.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    IncreasePositive electroencephalographic changes
    Study

    n = 60

    Comparator
    Microcurrent reflexology without Cortexin
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    10 mg · intramuscular · Two courses, 10 injections per courseAs given in this study (human).

    Measurements

    Positive EEG changes
    71%
    Cortexin plus reflexology
    Positive EEG changes
    53%
    Reflexology alone

    Source sentences

    Summary
    Positive changes in the encephalon functional status according to electroencephalography results were found in 21 patients (71%) of the first group and in 16 patients (53%) of the second group.
    7 context sentences
    Summary · context
    Sixty patients with the diagnosis of cerebral palsy with hemiparesis at the age from 2 to 7 years were treated.
    Summary · context
    All 60 patients had conventional treatment including massage and exercise therapy.
    Summary · context
    Patients were divided into 2 randomized groups.
    Summary · context
    The patients of the first group were given 3 sets of microcurrent reflexology sessions and 2 courses of treatment with cortexin.
    Summary · context
    Patients of the second group were given reflexology treatments only.
    Summary · context
    Cortexin was introduced intramuscularly in dosage 10 mg.
    Summary · context
    The treatment included 10 injections.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:25 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.