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Study · In vitro (cells) · mouse · 2012

5 results

Tetrapeptide H-Ala-Glu-Asp-Arg-OH stimulates expression of cytoskeletal and nuclear matrix proteins.

Khavinson VKh, Lin'kova NS, Polyakova VO, Kvetnoy IM, Benberin VV, D'yakonov MM, Titkov YS

Bulletin of experimental biology and medicine1 Aug 2012Cited by 1 (Europe PMC)

PMID22977870 (opens in a new tab)DOI10.1007/s10517-012-1766-9 (opens in a new tab)PepBankPUB-22977870
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In mouse embryonic fibroblasts, Cardiogen increased actin expression within the reported cytoskeletal protein range.

    In plain wordsIn cells from mice, Cardiogen increased actin expression.

    Peptide
    Cardiogen (AEDR)
    Outcome
    IncreaseActin expression
    Study

    mousen: not reported in source

    cultured mouse embryonic fibroblasts
    Outcome group
    Receptor activity and mechanism · Whole body
    Studied dose
    Dose not stated

    Measurements

    Cytoskeletal protein expression fold change
    2 to 5 times
    reported result

    Source sentences

    Summary
    Tetrapeptide H-Ala-Glu-Asp-Arg-OH enhances the expression of cytoskeletal (actin, tubulin, vimentin) and nuclear matrix proteins (lamin A, lamin C) in cultured mouse embryonic fibroblasts by 2-5 and 2-3 times, respectively.
  2. 02LabIn vitro (cells)Mechanism

    In mouse embryonic fibroblasts, Cardiogen increased tubulin expression within the reported cytoskeletal protein range.

    In plain wordsIn cells from mice, Cardiogen increased tubulin expression.

    Peptide
    Cardiogen (AEDR)
    Outcome
    IncreaseTubulin expression
    Study

    mousen: not reported in source

    cultured mouse embryonic fibroblasts
    Outcome group
    Receptor activity and mechanism · Whole body
    Studied dose
    Dose not stated

    Measurements

    Cytoskeletal protein expression fold change
    2 to 5 times
    reported result

    Source sentences

    Summary
    Tetrapeptide H-Ala-Glu-Asp-Arg-OH enhances the expression of cytoskeletal (actin, tubulin, vimentin) and nuclear matrix proteins (lamin A, lamin C) in cultured mouse embryonic fibroblasts by 2-5 and 2-3 times, respectively.
  3. 03LabIn vitro (cells)Mechanism

    In mouse embryonic fibroblasts, Cardiogen increased vimentin expression within the reported cytoskeletal protein range.

    In plain wordsIn cells from mice, Cardiogen increased vimentin expression.

    Peptide
    Cardiogen (AEDR)
    Outcome
    IncreaseVimentin expression
    Study

    mousen: not reported in source

    cultured mouse embryonic fibroblasts
    Outcome group
    Receptor activity and mechanism · Whole body
    Studied dose
    Dose not stated

    Measurements

    Cytoskeletal protein expression fold change
    2 to 5 times
    reported result

    Source sentences

    Summary
    Tetrapeptide H-Ala-Glu-Asp-Arg-OH enhances the expression of cytoskeletal (actin, tubulin, vimentin) and nuclear matrix proteins (lamin A, lamin C) in cultured mouse embryonic fibroblasts by 2-5 and 2-3 times, respectively.
  4. 04LabIn vitro (cells)Mechanism

    In mouse embryonic fibroblasts, Cardiogen increased lamin A expression within the reported nuclear matrix protein range.

    In plain wordsIn cells from mice, Cardiogen increased lamin A expression.

    Peptide
    Cardiogen (AEDR)
    Outcome
    IncreaseLamin A expression
    Study

    mousen: not reported in source

    cultured mouse embryonic fibroblasts
    Outcome group
    Receptor activity and mechanism · Whole body
    Studied dose
    Dose not stated

    Measurements

    Nuclear matrix protein expression fold change
    2 to 3 times
    reported result

    Source sentences

    Summary
    Tetrapeptide H-Ala-Glu-Asp-Arg-OH enhances the expression of cytoskeletal (actin, tubulin, vimentin) and nuclear matrix proteins (lamin A, lamin C) in cultured mouse embryonic fibroblasts by 2-5 and 2-3 times, respectively.
  5. 05LabIn vitro (cells)Mechanism

    In mouse embryonic fibroblasts, Cardiogen increased lamin C expression within the reported nuclear matrix protein range.

    In plain wordsIn cells from mice, Cardiogen increased lamin C expression.

    Peptide
    Cardiogen (AEDR)
    Outcome
    IncreaseLamin C expression
    Study

    mousen: not reported in source

    cultured mouse embryonic fibroblasts
    Outcome group
    Receptor activity and mechanism · Whole body
    Studied dose
    Dose not stated

    Measurements

    Nuclear matrix protein expression fold change
    2 to 3 times
    reported result

    Source sentences

    Summary
    Tetrapeptide H-Ala-Glu-Asp-Arg-OH enhances the expression of cytoskeletal (actin, tubulin, vimentin) and nuclear matrix proteins (lamin A, lamin C) in cultured mouse embryonic fibroblasts by 2-5 and 2-3 times, respectively.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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