Skip to content

Study · Ex vivo tissue · rat · 2012

1 result

Sertoli-secreted FGF-2 induces PFKFB4 isozyme expression in mouse spermatogenic cells by activation of the MEK/ERK/CREB pathway.

Gómez M, Manzano A, Figueras A, Viñals F, Ventura F, Rosa JL, Bartrons R, Navarro-Sabaté À

American journal of physiology. Endocrinology and metabolism17 Jul 2012Cited by 20 (Europe PMC)

PMID22811469 (opens in a new tab)DOI10.1152/ajpendo.00381.2011 (opens in a new tab)PepBankPUB-22811469
Publisher pagePubMedAsk about this study
Jump to 1 result

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueMechanism

    In adult rat testes, degarelix treatment reduced PFKFB4 expression in germ cells.

    In plain wordsIn lab tests with adult rat testes, degarelix reduced PFKFB4 expression in germ cells.

    Peptide
    Degarelix
    Outcome
    DecreaseGerm-cell PFKFB4 expression
    Study

    ratn: not reported in source

    Adult rat testes
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In addition, adult rat testes treated with the GnRH antagonist Degarelix exhibited a reduction in the expression of PFKFB4 in germ cells.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:34 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.