Acute tubulointerstitial nephritis following treatment with exenatide.

In a man with type 2 diabetes, estimated glomerular filtration rate declined from 59 to 39 after exenatide treatment.

In plain wordsIn one man, kidney filtration declined after exenatide treatment.

Measurements

eGFR

59 ml min(-1) 1.73 m(-2)

before deterioration

eGFR

39 ml min(-1) 1.73 m(-2)

after 2 months

Source sentences

In the same man, estimated glomerular filtration rate deteriorated to 16 despite exenatide cessation.

In plain wordsIn one man, kidney filtration continued to decline after exenatide stopped.

Measurements

eGFR

16 ml min(-1) 1.73 m(-2)

after exenatide cessation

Source sentences

In a man treated with exenatide, biopsy showed active diffuse tubulointerstitial nephritis with eosinophil infiltration.

In plain wordsIn one man treated with exenatide, a kidney biopsy showed inflammation with eosinophils.

Source sentences

In one man who developed biopsy-proven tubulointerstitial nephritis after starting exenatide, kidney function recovered incompletely after months of prednisolone.

In plain wordsIn one man whose kidney inflammation followed exenatide treatment, kidney function recovered only partly after months of prednisolone.

Source sentences