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Study · Animal study (in vivo) · rat · 2011

3 results

[Experimental hemorrhagic stroke: the effect of the peptide preparation cortexin in the formation of Hb-NO-complexes and other blood paramagnetic centers].

Reutov VP, Baĭder LM, Kuropteva ZV, Krushinskiĭ AL, Kuzenkov VS, Moldaliev ZhT, Granstrem OK

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova1 Jan 2011

PMID22224248 (opens in a new tab)PepBankPUB-22224248
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rats with experimental hemorrhagic stroke, cortexin reduced blood Hb-NO-complex formation.

    In plain wordsIn rats with experimental hemorrhagic stroke, cortexin reduced blood Hb-NO-complex formation.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    DecreaseBlood Hb-NO-complex formation
    Study

    ratn: not reported in source

    Krushynsky-Molodkina rats with acoustic stress-induced hemorrhagic stroke
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Cortexin substantially reduces the formation of Hb-NO-complexes and, therefore, the level of nitride oxide while the contents of transferrin and methemoglobin remain intact.
    1 context sentence
    Summary · context
    Using electronic paramagnetic resonance (EPR), we studied the effect of the peptide cortexin on the content of hemoglobin nitrozyl complexes (Hb-NO-complexes) and other paramagnetic centers (transferrin, methemoglobin) in the blood of rats of Krushynsky-Molodkina line in the experimental hemorrhagic…
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats with experimental hemorrhagic stroke, cortexin left blood transferrin content unchanged.

    In plain wordsIn rats with experimental hemorrhagic stroke, cortexin left blood transferrin content unchanged.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    No significant changeBlood transferrin content
    Study

    ratn: not reported in source

    Krushynsky-Molodkina rats with acoustic stress-induced hemorrhagic stroke
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Cortexin substantially reduces the formation of Hb-NO-complexes and, therefore, the level of nitride oxide while the contents of transferrin and methemoglobin remain intact.
    1 context sentence
    Summary · context
    Using electronic paramagnetic resonance (EPR), we studied the effect of the peptide cortexin on the content of hemoglobin nitrozyl complexes (Hb-NO-complexes) and other paramagnetic centers (transferrin, methemoglobin) in the blood of rats of Krushynsky-Molodkina line in the experimental hemorrhagic…
  3. 03AnimalAnimal study (in vivo)Mechanism

    In rats with experimental hemorrhagic stroke, cortexin left blood methemoglobin content unchanged.

    In plain wordsIn rats with experimental hemorrhagic stroke, cortexin left blood methemoglobin content unchanged.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    No significant changeBlood methemoglobin content
    Study

    ratn: not reported in source

    Krushynsky-Molodkina rats with acoustic stress-induced hemorrhagic stroke
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Cortexin substantially reduces the formation of Hb-NO-complexes and, therefore, the level of nitride oxide while the contents of transferrin and methemoglobin remain intact.
    1 context sentence
    Summary · context
    Using electronic paramagnetic resonance (EPR), we studied the effect of the peptide cortexin on the content of hemoglobin nitrozyl complexes (Hb-NO-complexes) and other paramagnetic centers (transferrin, methemoglobin) in the blood of rats of Krushynsky-Molodkina line in the experimental hemorrhagic…

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:25 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

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