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Study · Animal study (in vivo) · rat · 2011

1 result

BPC 157 therapy to detriment sphincters failure-esophagitis-pancreatitis in rat and acute pancreatitis patients low sphincters pressure.

Petrovic I, Dobric I, Drmic D, Sever M, Klicek R, Radic B, Brcic L, Kolenc D, Zlatar M, Kunjko K, Jurcic D, Martinac M and 5 more

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Rasic Z, Boban Blagaic A, Romic Z, Seiwerth S, Sikiric P

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society1 Oct 2011Cited by 15 (Europe PMC)

PMID22204800 (opens in a new tab)PepBankPUB-22204800
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats with combined esophagitis, sphincter failure and acute pancreatitis, BPC‑157 therapies counteracted the lesions.

    In plain wordsIn rats with gut valve failure, food pipe and pancreas inflammation, BPC‑157 counteracted the damage.

    Peptide
    BPC-157
    Outcome
    DecreaseEsophagitis, sphincter failure and acute pancreatitis lesions
    Study

    ratn: not reported in source

    esophagitis, sphincter failure and acute pancreatitis
    Outcome group
    Gastrointestinal protection · Gastrointestinal
    Studied dose
    10 μg/kg, 10 ng/kg · intraperitoneal or drinking waterAs given in this study (rat).

    Source sentences

    Summary
    Counteraction occurred by BPC 157 therapies.
    2 context sentences
    Summary · context
    What's more, these lesions (esophagitis, sphincter failure, acute pancreatitis when combined) aggravate each other (tubes into sphincters and ligated bile duct).
    Summary · context
    The esophagitis-sphincter failure procedure (i.e., insertion of the tubes into the sphincters, lower esophageal and pyloric) and acute pancreatitis procedure (i.e., bile duct ligation) were combined in rats.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:19 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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