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Study · Measured the body's own peptide · 2012

5 results

Central distribution of kiss2 neurons and peri-pubertal changes in their expression in the brain of male and female red seabream Pagrus major.

Shimizu Y, Tomikawa J, Hirano K, Nanikawa Y, Akazome Y, Kanda S, Kazeto Y, Okuzawa K, Uenoyama Y, Ohkura S, Tsukamura H, Maeda K, Gen K, Oka Y, Yamamoto N

General and comparative endocrinology7 Dec 2011Cited by 30 (Europe PMC)

PMID22166815 (opens in a new tab)DOI10.1016/j.ygcen.2011.11.038 (opens in a new tab)PepBankPUB-22166815
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In male and female red seabream, the number of kiss2-expressing neurons in the NRLd was larger in the first spawning season than after spawning.

    In plain wordsIn red seabream of both sexes, natural kiss2 nerve cells in one brain area were more numerous in the first spawning season than after spawning.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseKiss2 neuron number in NRLd, first spawning season
    Study

    red seabream (Pagrus major)n: not reported in source

    Hypothalamic kiss2 neurons
    Comparator
    Post-spawning fish
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    The number of kiss2-expressing neurons in the NRLd was larger during the first spawning season in both males and females compared with fish in the post-spawning periods.
    1 context sentence
    Summary · context
    The amino acid sequence deduced from the red seabream kiss2 contained a highly conserved 10-amino-acid residue, Kiss2(10) or kp-10.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In male red seabream, the number of kiss2 neurons in the NRLd of maturing fish was larger than in post-spawning fish.

    In plain wordsIn male red seabream, the body's own kiss2 nerve cells in one brain area were more numerous in maturing fish than after spawning.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseKiss2 neuron number in NRLd, maturing males
    Study

    red seabream (Pagrus major)n: not reported in source

    Hypothalamic kiss2 neurons
    Comparator
    Post-spawning fish
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    In males the number of kiss2 neurons in the NRLd of maturing fish was also larger than those in the post-spawning periods.
    1 context sentence
    Summary · context
    The amino acid sequence deduced from the red seabream kiss2 contained a highly conserved 10-amino-acid residue, Kiss2(10) or kp-10.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In male red seabream, the number of kiss2 neurons in the NRLv changed in a similar pattern to the NRLd.

    In plain wordsIn male red seabream, the body's own kiss2 nerve cells in a second brain area changed in the same pattern as in the first.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseKiss2 neuron number in NRLv, males
    Study

    red seabream (Pagrus major)n: not reported in source

    Hypothalamic kiss2 neurons
    Comparator
    Post-spawning fish
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    In males the number of kiss2 neurons in the NRLv showed a similar pattern of changes to that of NRLd, while significant changes were not detected for females.
    1 context sentence
    Summary · context
    The amino acid sequence deduced from the red seabream kiss2 contained a highly conserved 10-amino-acid residue, Kiss2(10) or kp-10.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In female red seabream, no significant change in the number of kiss2 neurons in the NRLv was detected.

    In plain wordsIn female red seabream, the body's own kiss2 nerve cells in this brain area showed no significant change.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeKiss2 neuron number in NRLv, females
    Study

    red seabream (Pagrus major)n: not reported in source

    Hypothalamic kiss2 neurons
    Comparator
    Post-spawning fish
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    In males the number of kiss2 neurons in the NRLv showed a similar pattern of changes to that of NRLd, while significant changes were not detected for females.
    1 context sentence
    Summary · context
    The amino acid sequence deduced from the red seabream kiss2 contained a highly conserved 10-amino-acid residue, Kiss2(10) or kp-10.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  5. 05AnimalEndogenous levelAnimal study (in vivo)Other

    In red seabream, kiss2 mRNA-expressing neurons were found in the NRLd and NRLv of the hypothalamus, and in some fish in the preoptic area and nucleus ventralis tuberis.

    In plain wordsIn red seabream, the body's own kiss2 nerve cells were found mainly in two parts of the hypothalamus.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableDistribution of kiss2 neurons in the brain
    Study

    red seabream (Pagrus major)n: not reported in source

    Hypothalamic kiss2 neurons
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    Neurons that express kiss2 mRNA were distributed in the dorsal (NRLd) and ventral (NRLv) parts of nucleus recessi lateralis in the hypothalamus. In some fish a few kiss2-expressing neurons were detected in the preoptic area and nucleus ventralis tuberis.
    1 context sentence
    Summary · context
    The amino acid sequence deduced from the red seabream kiss2 contained a highly conserved 10-amino-acid residue, Kiss2(10) or kp-10.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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