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Study · Measured the body's own peptide · 2011

4 results

Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus.

Porteous R, Petersen SL, Yeo SH, Bhattarai JP, Ciofi P, de Tassigny XD, Colledge WH, Caraty A, Herbison AE

The Journal of comparative neurology1 Dec 2011Cited by 64 (Europe PMC)

PMID21800299 (opens in a new tab)DOI10.1002/cne.22716 (opens in a new tab)PepBankPUB-21800299
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In adult female mice, no evidence was found that RP3V kisspeptin neurons express neurotensin or CCK.

    In plain wordsIn female mice, the body's own kisspeptin nerve cells in this brain area did not carry neurotensin or CCK.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableNeurotensin and CCK in RP3V kisspeptin neurons
    Study

    mousen: not reported in source

    Adult female mouse hypothalamus (RP3V)
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Source sentences

    Summary
    No evidence was found for expression of neurotensin or CCK by RP3V kisspeptin neurons
    1 context sentence
    Summary · context
    Subsequent experiments, using a new kisspeptin-10 antibody raised in sheep, examined the relationship of these neuropeptides to kisspeptin neurons.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In adult female mice, 7% of RP3V kisspeptin neurons and 21% of RP3V galanin neurons were dual-labeled for kisspeptin and galanin.

    In plain wordsIn female mice, some of the body's own kisspeptin nerve cells in this brain area also carried galanin.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableGalanin co-expression in RP3V kisspeptin neurons
    Study

    mousen: not reported in source

    Adult female mouse hypothalamus (RP3V)
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Measurements

    Dual-labeled share of kisspeptin neurons
    7%
    kisspeptin/galanin, RP3V
    Dual-labeled share of galanin neurons
    21%
    kisspeptin/galanin, RP3V

    Source sentences

    Summary
    Dual-labeled RP3V kisspeptin/galanin cells represented 7% of all kisspeptin and 21% of all galanin neurons
    1 context sentence
    Summary · context
    Subsequent experiments, using a new kisspeptin-10 antibody raised in sheep, examined the relationship of these neuropeptides to kisspeptin neurons.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In adult female mice, 28-38% of RP3V kisspeptin neurons and 58-68% of mENK neurons were dual-labeled for kisspeptin and met-enkephalin, depending on location.

    In plain wordsIn female mice, many of the body's own kisspeptin nerve cells in this brain area also carried met-enkephalin.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableMet-enkephalin co-expression in RP3V kisspeptin neurons
    Study

    mousen: not reported in source

    Adult female mouse hypothalamus (RP3V)
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Measurements

    Dual-labeled share of kisspeptin neurons
    28 to 38%
    kisspeptin/mENK, AVPV or PVpo
    Dual-labeled share of mENK neurons
    58 to 68%
    kisspeptin/mENK, AVPV or PVpo

    Source sentences

    Summary
    whereas dual-labeled kisspeptin/mENK cells represented 28-38% of kisspeptin neurons and 58-68% of the mENK population, depending on location within the AVPV or PVpo
    1 context sentence
    Summary · context
    Subsequent experiments, using a new kisspeptin-10 antibody raised in sheep, examined the relationship of these neuropeptides to kisspeptin neurons.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In adult female mice, kisspeptin neurons in the arcuate nucleus expressed galanin but not met-enkephalin.

    In plain wordsIn female mice, the body's own kisspeptin nerve cells in the arcuate nucleus carried galanin but not met-enkephalin.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableGalanin and met-enkephalin in arcuate kisspeptin neurons
    Study

    mousen: not reported in source

    Adult female mouse hypothalamus (RP3V)
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Source sentences

    Summary
    Kisspeptin neurons in the arcuate nucleus were also found to express galanin but not mENK.
    1 context sentence
    Summary · context
    Subsequent experiments, using a new kisspeptin-10 antibody raised in sheep, examined the relationship of these neuropeptides to kisspeptin neurons.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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