In a thioflavin-T assay, a humanin derivative with two D-Ser residues formed fibrils more readily than wild-type humanin or derivatives with single D-Ser residues.
In plain wordsIn lab tests, a humanin derivative with two D-Ser residues formed fibrils more readily than normal humanin or single D-Ser versions.
- Peptide
- Humanin
- Outcome
- IncreaseFibril formation of humanin with two D-Ser residues
- Study
n: not reported in source
Thioflavin-T assay of synthetic peptides- Comparator
- Wild-type HN and HNs with single D-Ser residues
- Outcome group
- Receptor activity and mechanism · Nervous system and cognition
Source sentences
we found that an HN derivative that contained two isomerized D-Ser residues had a greater tendency to form fibrils than did wild-type HN or HNs containing single D-Ser residues.
In this study, Humanin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Humanin.