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Study · Measured the body's own peptide · 2012

3 results

Striking neuronal thymosin beta 4 expression in the deep layers of the mouse superior colliculus after monocular deprivation.

Paulussen M, Arckens L

Brain structure & function31 May 2011Cited by 6 (Europe PMC)

PMID21626305 (opens in a new tab)DOI10.1007/s00429-011-0330-0 (opens in a new tab)PepBankPUB-21626305
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In mice, the number of Tβ4-immunoreactive neurons in the deep superior colliculus increased significantly with survival time after enucleation.

    In plain wordsIn mice, the number of nerve cells with the body's own Tβ4 rose over time after one eye was removed.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseNumber of Tβ4-immunoreactive neurons in deep superior colliculus
    Study

    mousen: not reported in source

    superior colliculus after monocular enucleation
    Comparator
    Control mice
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    whereas their number increased significantly with post-enucleation survival time
    1 context sentence
    Summary · context
    In the present study, we quantitatively analyzed the immunocytochemical expression pattern of Tβ4 in the superior colliculus (SC) of the adult mouse following monocular enucleation.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In mice, the total extent of the neuritic tree of Tβ4-immunoreactive neurons increased with survival time after enucleation.

    In plain wordsIn mice, nerve cells with the body's own Tβ4 grew larger branching trees over time after one eye was removed.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseExtent of the neuritic tree of Tβ4-immunoreactive neurons
    Study

    mousen: not reported in source

    superior colliculus after monocular enucleation
    Comparator
    Control mice
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    whereas their number increased significantly with post-enucleation survival time, as well as the total extent of the neuritic tree and its degree of branching.
    1 context sentence
    Summary · context
    In the present study, we quantitatively analyzed the immunocytochemical expression pattern of Tβ4 in the superior colliculus (SC) of the adult mouse following monocular enucleation.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In mice, the degree of branching of Tβ4-immunoreactive neurons increased with survival time after enucleation.

    In plain wordsIn mice, nerve cells with the body's own Tβ4 became more branched over time after one eye was removed.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseDegree of branching of Tβ4-immunoreactive neurons
    Study

    mousen: not reported in source

    superior colliculus after monocular enucleation
    Comparator
    Control mice
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    whereas their number increased significantly with post-enucleation survival time, as well as the total extent of the neuritic tree and its degree of branching.
    1 context sentence
    Summary · context
    In the present study, we quantitatively analyzed the immunocytochemical expression pattern of Tβ4 in the superior colliculus (SC) of the adult mouse following monocular enucleation.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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