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Study · Measured the body's own peptide · 2011

2 results

Markers of progenitor cell recruitment and differentiation rise early during ischemia and continue during resuscitation in a porcine acute ischemia model.

Shah AP, Youngquist ST, McClung CD, Tzvetkova E, Hanif MA, Rosborough JP, Niemann JT

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research20 Feb 2011Cited by 8 (Europe PMC)

PMID21332365 (opens in a new tab)PMCIDPMC3104289 (opens in a new tab)DOI10.1089/jir.2010.0133 (opens in a new tab)PepBankPUB-21332365
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In swine with balloon occlusion of the left anterior descending coronary artery, plasma levels of the body's own thymosin beta‑4 rose in a time-dependent way during ischemia.

    In plain wordsIn pigs with a blocked heart artery, the body's own thymosin beta‑4 in blood rose over time during the blockage.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreasePlasma TB4 during myocardial ischemia
    Study

    swinen = 15

    Balloon occlusion of the proximal left anterior descending coronary artery
    Outcome group
    Heart function · Cardiovascular

    Source sentences

    Summary
    TB4, VEGF, and MMP-9 demonstrated a statistically significant, time-dependent increase in concentration during ischemia.
    1 context sentence
    Summary · context
    Fifteen anesthetized and instrumented domestic swine underwent balloon occlusion of the proximal left anterior descending coronary artery.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In swine, after cardiac arrest and during the first 15 minutes of resuscitation, the rise in plasma levels of the body's own thymosin beta‑4 accelerated compared with the ischemic period before arrest.

    In plain wordsIn pigs, the body's own thymosin beta‑4 in blood rose faster during resuscitation than during the blockage before cardiac arrest.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreasePlasma TB4 trajectory during resuscitation
    Study

    swinen = 15

    Balloon occlusion of the proximal left anterior descending coronary artery
    Outcome group
    Heart function · Cardiovascular

    Source sentences

    Summary
    Following arrest and throughout the first 15 min of resuscitation, MMP-9 had an unchanged rate of rise when compared with the prearrest, ischemic period, with VEGF showing a deceleration in its time-dependent concentration trajectory and TB4 demonstrating an acceleration.
    1 context sentence
    Summary · context
    Fifteen anesthetized and instrumented domestic swine underwent balloon occlusion of the proximal left anterior descending coronary artery.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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