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Study · Measured the body's own peptide · 2011

2 results

Elevated expression of thymosin β4, vascular endothelial growth factor (VEGF), and hypoxia inducible factor (HIF)-1α in early-stage cervical cancers.

Kim NS, Kang YJ, Jo JO, Kim HY, Oh YR, Kim YO, Jung MH, Ock MS, Cha HJ

Pathology oncology research : POR7 Jan 2011Cited by 23 (Europe PMC)

PMID21213129 (opens in a new tab)DOI10.1007/s12253-010-9327-x (opens in a new tab)PepBankPUB-21213129
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In patients with cervical cancer, tissue expression of the body's own thymosin beta‑4 was very weak at stages 0 to 1A and significantly higher at stage 1B.

    In plain wordsIn people with cervical cancer, the body's own thymosin beta‑4 was low in early-stage tumors and higher at stage 1B.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseTB-4 expression by cervical cancer stage
    Study

    n = 42

    Comparator
    Early stages (0 to 1A)
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    The expression levels of TB-4, VEGF, and HIF-1α were very weak at early cancer stages (stages 0 to 1A) but significantly increased at stage 1B.
    1 context sentence
    Summary · context
    Expression patterns of TB-4, VEGF, and HIF-1α were studied with tissue microarray containing 42 samples of cervical cancers.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In patients with cervical cancer, expression of the body's own thymosin beta‑4 was lower in primary tumors with lymph node metastasis and in their lymph node metastases than in tumors without lymph node metastasis.

    In plain wordsIn people with cervical cancer, the body's own thymosin beta‑4 was lower in tumors with lymph node spread than in tumors without.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    DecreaseTB-4 expression in tumors with lymph node metastasis
    Study

    n: not reported in source

    Comparator
    Tumors without lymph node metastasis
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    The expression levels of TB-4, VEGF, and HIF-1α in primary tumors with lymph node metastasis and their metastatic tumors in lymph node were less than in tumors without lymph node metastasis.
    2 context sentences
    Summary · context
    In addition, 15 cervical cancers and metastatic tumors in lymph nodes from patients who have metastatic tumors were also analyzed to confirm the role of TB-4, VEGF, and HIF -1α in cervical cancer metastasis.
    Summary · context
    Expression patterns of TB-4, VEGF, and HIF-1α were studied with tissue microarray containing 42 samples of cervical cancers.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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