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Study · Animal study (in vivo) · rat · 2011

3 results

Protective effect of carnosine on adriamycin-induced oxidative heart damage in rats.

Ozdoğan K, Taşkın E, Dursun N

Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology24 Dec 2010Cited by 28 (Europe PMC)

PMID21183419 (opens in a new tab)DOI10.5152/akd.2011.003 (opens in a new tab)PepBankPUB-21183419
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, carnosine significantly attenuated adriamycin-induced cardiac dysfunction and normalized ventricular function.

    In plain wordsIn rats, carnosine normalized ventricular function compared with adriamycin alone.

    Peptide
    L-carnosine
    Outcome
    Not applicableVentricular function
    Study

    ratn: not reported in source

    Female Sprague Dawley rats with adriamycin-induced cardiac damage
    Comparator
    Adriamycin alone
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated · intravenous · One week before and one week with adriamycin treatmentAs given in this study (rat).

    Source sentences

    Summary
    Carnosine treatment caused significant attenuation (p=0.05) of cardiac dysfunction induced by adriamycin (CAR+ADR), revealed by normalization of the ventricular function, ECG and biochemical variables.
    3 context sentences
    Summary · context
    The present study examined the antioxidant protective effects of carnosine (CAR) on adriamycin-induced cardiac damage in rats.
    Summary · context
    Female Sprague Dawley rats were divided into four groups.
    Summary · context
    Carnosine was given one week before adriamycin treatment and following one week with adriamycin treatment.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, carnosine normalized ECG variables after adriamycin-induced cardiac dysfunction.

    In plain wordsIn rats, carnosine normalized ECG variables compared with adriamycin alone.

    Peptide
    L-carnosine
    Outcome
    Not applicableElectrocardiogram
    Study

    ratn: not reported in source

    Female Sprague Dawley rats with adriamycin-induced cardiac damage
    Comparator
    Adriamycin alone
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated · intravenous · One week before and one week with adriamycin treatmentAs given in this study (rat).

    Source sentences

    Summary
    Carnosine treatment caused significant attenuation (p=0.05) of cardiac dysfunction induced by adriamycin (CAR+ADR), revealed by normalization of the ventricular function, ECG and biochemical variables.
    3 context sentences
    Summary · context
    The present study examined the antioxidant protective effects of carnosine (CAR) on adriamycin-induced cardiac damage in rats.
    Summary · context
    Female Sprague Dawley rats were divided into four groups.
    Summary · context
    Carnosine was given one week before adriamycin treatment and following one week with adriamycin treatment.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats, carnosine normalized biochemical variables after adriamycin-induced cardiac dysfunction.

    In plain wordsIn rats, carnosine normalized biochemical variables compared with adriamycin alone.

    Peptide
    L-carnosine
    Outcome
    Not applicableBiochemical variables
    Study

    ratn: not reported in source

    Female Sprague Dawley rats with adriamycin-induced cardiac damage
    Comparator
    Adriamycin alone
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated · intravenous · One week before and one week with adriamycin treatmentAs given in this study (rat).

    Source sentences

    Summary
    Carnosine treatment caused significant attenuation (p=0.05) of cardiac dysfunction induced by adriamycin (CAR+ADR), revealed by normalization of the ventricular function, ECG and biochemical variables.
    3 context sentences
    Summary · context
    The present study examined the antioxidant protective effects of carnosine (CAR) on adriamycin-induced cardiac damage in rats.
    Summary · context
    Female Sprague Dawley rats were divided into four groups.
    Summary · context
    Carnosine was given one week before adriamycin treatment and following one week with adriamycin treatment.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

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