Synchronization of ovulation and fertility in weaned sows treated with intravaginal triptorelin is influenced by timing of administration and follicle size.

Knox RV, Willenburg KL, Rodriguez-Zas SL, Greger DL, Hafs HD, Swanson ME

Theriogenology30 Oct 2010Cited by 35 (Europe PMC)

PMID21040957DOI10.1016/j.theriogenology.2010.09.001PepBankPUB-21040957

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study10

6 results from studies that gave the peptide. No result from this study comes from people.

01AnimalAnimal study (in vivo)Efficacy outcome
In sows, triptorelin at 96 h after weaning increased ovulation by 48 h versus controls.
In plain wordsIn sows, triptorelin at 96 h after weaning increased ovulation by 48 h compared with untreated controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
IncreaseOvulation by 48 hours with TG-96
Study
pign: not reported in source
Weaned sows
Comparator
Untreated control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
100 μg · intravaginalAs given in this study (pig).
Measurements
Ovulation
57.9%
TG-96
Source sentences
Summary
Ovulation by 48 h post-treatment tended to be affected by treatment (P = 0.08) and more (P 0.10).
2 context sentences(design, population, supporting numbers)
Summary · context
A 100 μg dose of triptorelin was tested for synchronizing ovulation in sows.
Summary · context
In Experiment 1, conducted in April through June, sows (n = 125) were assigned to Control (untreated), TG-96 (Triptorelin Gel (TG) given intravaginally at 96 h post-weaning), or TG-E (given intravaginally at estrus).
Report a problemFND-2104095701
02AnimalAnimal study (in vivo)Efficacy outcome
In sows, triptorelin at estrus did not significantly alter ovulation by 48 h versus controls.
In plain wordsIn sows, triptorelin at estrus did not significantly change ovulation by 48 h compared with controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeOvulation by 48 hours with TG-E
Study
pign: not reported in source
Weaned sows
Comparator
Untreated control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
100 μg · intravaginalAs given in this study (pig).
Source sentences
Summary
Ovulation by 48 h post-treatment tended to be affected by treatment (P = 0.08) and more (P 0.10).
2 context sentences(design, population, supporting numbers)
Summary · context
A 100 μg dose of triptorelin was tested for synchronizing ovulation in sows.
Summary · context
In Experiment 1, conducted in April through June, sows (n = 125) were assigned to Control (untreated), TG-96 (Triptorelin Gel (TG) given intravaginally at 96 h post-weaning), or TG-E (given intravaginally at estrus).
Report a problemFND-2104095702
03AnimalAnimal study (in vivo)Efficacy outcome
In sows, triptorelin at 96 h after weaning reduced estrus duration to 51 h versus 65 h in controls.
In plain wordsIn sows, triptorelin at 96 h reduced estrus duration compared with untreated controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseEstrus duration with TG-96 in experiment 1
Study
pign: not reported in source
Weaned sows
Comparator
Untreated control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
100 μg · intravaginalAs given in this study (pig).
Source sentences
Summary
Duration of estrus was reduced (P < 0.005) in TG-96 (51 h) and TG-E (58 h) compared to Controls (65 h).
2 context sentences(design, population, supporting numbers)
Summary · context
A 100 μg dose of triptorelin was tested for synchronizing ovulation in sows.
Summary · context
In Experiment 1, conducted in April through June, sows (n = 125) were assigned to Control (untreated), TG-96 (Triptorelin Gel (TG) given intravaginally at 96 h post-weaning), or TG-E (given intravaginally at estrus).
Report a problemFND-2104095703
04AnimalAnimal study (in vivo)Efficacy outcome
In sows, triptorelin at estrus reduced estrus duration to 58 h versus 65 h in controls.
In plain wordsIn sows, triptorelin at estrus reduced estrus duration compared with untreated controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseEstrus duration with TG-E
Study
pign: not reported in source
Weaned sows
Comparator
Untreated control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
100 μg · intravaginalAs given in this study (pig).
Source sentences
Summary
Duration of estrus was reduced (P < 0.005) in TG-96 (51 h) and TG-E (58 h) compared to Controls (65 h).
2 context sentences(design, population, supporting numbers)
Summary · context
A 100 μg dose of triptorelin was tested for synchronizing ovulation in sows.
Summary · context
In Experiment 1, conducted in April through June, sows (n = 125) were assigned to Control (untreated), TG-96 (Triptorelin Gel (TG) given intravaginally at 96 h post-weaning), or TG-E (given intravaginally at estrus).
Report a problemFND-2104095704
05AnimalAnimal study (in vivo)Efficacy outcome
In sows, TG-96 reduced estrus duration in the second experiment.
In plain wordsIn sows, triptorelin at 96 h reduced estrus duration compared with controls in the second experiment.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseEstrus duration in experiment 2
Study
pign: not reported in source
Weaned sows
Comparator
Untreated control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
100 μg · intravaginalAs given in this study (pig).
Source sentences
Summary
The TG-96 treatment reduced duration of estrus (P = 0.03), but treatment did not affect estrus expression, farrowing rate or total pigs born.
2 context sentences(design, population, supporting numbers)
Summary · context
Experiment 2 was conducted in August through September using 503 weaned sows.
Summary · context
A 100 μg dose of triptorelin was tested for synchronizing ovulation in sows.
Report a problemFND-2104095707
06AnimalAnimal study (in vivo)Efficacy outcome
In sows, TG-96 did not affect estrus expression in the second experiment.
In plain wordsIn sows, triptorelin did not change estrus expression compared with controls in the second experiment.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeEstrus expression in experiment 2
Study
pign: not reported in source
Weaned sows
Comparator
Untreated control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
100 μg · intravaginalAs given in this study (pig).
Source sentences
Summary
The TG-96 treatment reduced duration of estrus (P = 0.03), but treatment did not affect estrus expression, farrowing rate or total pigs born.
2 context sentences(design, population, supporting numbers)
Summary · context
Experiment 2 was conducted in August through September using 503 weaned sows.
Summary · context
A 100 μg dose of triptorelin was tested for synchronizing ovulation in sows.
Report a problemFND-2104095708

Studies that did not test the peptide alone4

In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Triptorelin (Trelstar, Decapeptyl).

07AnimalNot a test of Triptorelin (Trelstar, Decapeptyl) aloneAnimal study (in vivo)Efficacy outcome
In sows, triptorelin with timed insemination did not significantly change farrowing rate compared with controls in experiment 1.
In plain wordsIn sows, triptorelin with timed insemination did not significantly change farrowing rate compared with controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeFarrowing rate in experiment 1
Study
pign: not reported in source
Weaned sows
Comparator
Untreated control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
There was no treatment effect on farrowing rate (71%) or total born (10.4).
2 context sentences(design, population, supporting numbers)
Summary · context
In Experiment 1, conducted in April through June, sows (n = 125) were assigned to Control (untreated), TG-96 (Triptorelin Gel (TG) given intravaginally at 96 h post-weaning), or TG-E (given intravaginally at estrus).
Summary · context
A 100 μg dose of triptorelin was tested for synchronizing ovulation in sows.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-2104095705
08AnimalNot a test of Triptorelin (Trelstar, Decapeptyl) aloneAnimal study (in vivo)Efficacy outcome
In sows, triptorelin with timed insemination did not significantly change total pigs born compared with controls in experiment 1.
In plain wordsIn sows, triptorelin with timed insemination did not significantly change total pigs born compared with controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeTotal born in experiment 1
Study
pign: not reported in source
Weaned sows
Comparator
Untreated control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
There was no treatment effect on farrowing rate (71%) or total born (10.4).
2 context sentences(design, population, supporting numbers)
Summary · context
In Experiment 1, conducted in April through June, sows (n = 125) were assigned to Control (untreated), TG-96 (Triptorelin Gel (TG) given intravaginally at 96 h post-weaning), or TG-E (given intravaginally at estrus).
Summary · context
A 100 μg dose of triptorelin was tested for synchronizing ovulation in sows.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-2104095706
09AnimalNot a test of Triptorelin (Trelstar, Decapeptyl) aloneAnimal study (in vivo)Efficacy outcome
In sows, triptorelin with timed insemination did not significantly change farrowing rate compared with controls in experiment 2.
In plain wordsIn sows, triptorelin with timed insemination did not significantly change farrowing rate compared with controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeFarrowing rate in experiment 2
Study
pign: not reported in source
Weaned sows
Comparator
Untreated control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
The TG-96 treatment reduced duration of estrus (P = 0.03), but treatment did not affect estrus expression, farrowing rate or total pigs born.
2 context sentences(design, population, supporting numbers)
Summary · context
Experiment 2 was conducted in August through September using 503 weaned sows.
Summary · context
A 100 μg dose of triptorelin was tested for synchronizing ovulation in sows.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-2104095709
10AnimalNot a test of Triptorelin (Trelstar, Decapeptyl) aloneAnimal study (in vivo)Efficacy outcome
In sows, triptorelin with timed insemination did not significantly change total pigs born compared with controls in experiment 2.
In plain wordsIn sows, triptorelin with timed insemination did not significantly change total pigs born compared with controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeTotal pigs born in experiment 2
Study
pign: not reported in source
Weaned sows
Comparator
Untreated control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
The TG-96 treatment reduced duration of estrus (P = 0.03), but treatment did not affect estrus expression, farrowing rate or total pigs born.
2 context sentences(design, population, supporting numbers)
Summary · context
Experiment 2 was conducted in August through September using 503 weaned sows.
Summary · context
A 100 μg dose of triptorelin was tested for synchronizing ovulation in sows.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-2104095710

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
22 Oct 2026, 02:26 UTC
Study results updated
Version 1
21 Oct 2026, 18:59 UTC
First added · source update from Europe PMC

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