In biochemical tests, adding the C-terminal pointed end-capping helix of thymosin beta‑4 to tandem W domains changed their activity from actin filament nucleation to monomer sequestration.
In plain wordsIn lab tests, adding a part of thymosin beta‑4 to actin-binding domains changed their activity from starting actin filaments to holding actin monomers.
- Peptide
- Thymosin beta-4 (human)
- Outcome
- Not applicableActin nucleation versus monomer sequestration activity
- Study
n: not reported in source
- Outcome group
- Receptor activity and mechanism · Whole body
Source sentences
We finally show that the simple addition of the C-terminal pointed end-capping helix of thymosin β4 to tandem W domains can change their activity from actin filament nucleation to monomer sequestration.
In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).