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Study · Not a test of the peptide alone · 2010

1 result

Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1.

Brieger A, Adryan B, Wolpert F, Passmann S, Zeuzem S, Trojan J

Proteomics1 Sept 2010Cited by 16 (Europe PMC)

PMID20706999 (opens in a new tab)DOI10.1002/pmic.200900672 (opens in a new tab)PepBankPUB-20706999
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 01LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Mechanism

    Coimmunoprecipitation and colocalization experiments validated an interaction between MLH1 and thymosin beta‑4, among other cytoskeletal proteins.

    In plain wordsIn cells, lab tests showed that the MLH1 protein interacts with thymosin beta‑4.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableInteraction of MLH1 with thymosin beta 4
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Cancer

    Source sentences

    Summary
    Coimmunoprecipitation and colocalization experiments validated the interaction of MLH1 with these proteins.
    1 context sentence
    Summary · context
    Integration of our data with the "General Repository for Interaction Datasets" highlighted that MLH1 exhibits relationships to three interacting pairs of proteins involved in cytoskeletal and filament organization: Thymosin beta 4 and Actin gamma, Cathepsin B and Annexin A2 as well as Spectrin alpha and Desmin.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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