Molecular characterization, tissue distribution, and mRNA expression profiles of two Kiss genes in the adult male and female chub mackerel (Scomber japonicus) during different gonadal stages.

Selvaraj S, Kitano H, Fujinaga Y, Ohga H, Yoneda M, Yamaguchi A, Shimizu A, Matsuyama M

General and comparative endocrinology29 Jul 2010Cited by 74 (Europe PMC)

PMID20691652DOI10.1016/j.ygcen.2010.07.011PepBankPUB-20691652

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study11

No result from this study comes from a test of the peptide.

Natural levels measured9

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01AnimalEndogenous levelAnimal study (in vivo)Other
In adult chub mackerel, Kiss1 and Kiss2 transcripts were expressed in different tissues, measured as the fish's own gene expression.
In plain wordsIn chub mackerel, the body's own kisspeptin genes were active in different tissues.
Peptide
Kisspeptin-10
Outcome
Not applicableKiss1 and Kiss2 tissue distribution
Study
chub mackereln: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Tissue distribution analysis using quantitative real-time PCR (qRT-PCR) revealed that the Kiss1 and Kiss2 transcripts were expressed in different tissues of adult chub mackerel.
This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2069165201
02AnimalEndogenous levelAnimal study (in vivo)Other
In adult chub mackerel, Kiss1 and Kiss2 levels in adipose tissue differed between the sexes (sexually dimorphic expression).
In plain wordsIn chub mackerel, the body's own kisspeptin gene activity in fat tissue differed between males and females.
Peptide
Kisspeptin-10
Outcome
Not applicableKiss1 and Kiss2 expression in adipose tissue
Study
chub mackereln: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
In addition, their levels in the adipose tissue exhibited sexually dimorphic expression.
This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2069165202
03AnimalEndogenous levelAnimal study (in vivo)Other
In chub mackerel, brain Kiss1 and Kiss2 levels followed a different profile in males than in females across gonadal stages.
In plain wordsIn chub mackerel, the body's own kisspeptin gene activity in the brain followed a different pattern in males and females.
Peptide
Kisspeptin-10
Outcome
Not applicableKiss1 and Kiss2 expression in brain, male versus female
Study
chub mackereln: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Kiss1 and Kiss2 levels in the brain showed a differential expression profile between male and female fish.
This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2069165203
04AnimalEndogenous levelAnimal study (in vivo)Other
In male chub mackerel, brain Kiss1 levels decreased gradually from the immature stage to spermiation and were lowest after spawning.
In plain wordsIn male chub mackerel, the body's own kisspeptin gene activity in the brain fell from the immature stage to after spawning.
Peptide
Kisspeptin-10
Outcome
DecreaseKiss1 expression in brain of males across gonadal stages
Study
chub mackereln: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
In males, Kiss1 and Kiss2 levels gradually decreased from the immature stage to spermiation and reached a minimal level during the post-spawning period.
This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2069165204
05AnimalEndogenous levelAnimal study (in vivo)Other
In male chub mackerel, brain Kiss2 levels decreased gradually from the immature stage to spermiation and were lowest after spawning.
In plain wordsIn male chub mackerel, the body's own kisspeptin gene activity in the brain fell from the immature stage to after spawning.
Peptide
Kisspeptin-10
Outcome
DecreaseKiss2 expression in brain of males across gonadal stages
Study
chub mackereln: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
In males, Kiss1 and Kiss2 levels gradually decreased from the immature stage to spermiation and reached a minimal level during the post-spawning period.
This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2069165205
06AnimalEndogenous levelAnimal study (in vivo)Other
In female chub mackerel, brain Kiss1 levels did not vary significantly among gonadal stages.
In plain wordsIn female chub mackerel, the body's own kisspeptin gene activity in the brain did not change significantly across stages.
Peptide
Kisspeptin-10
Outcome
No significant changeKiss1 expression in brain of females across gonadal stages
Study
chub mackereln: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
In contrast, Kiss1 levels in the brain of females did not vary significantly among the different gonadal stages.
This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2069165206
07AnimalEndogenous levelAnimal study (in vivo)Other
In female chub mackerel, brain Kiss2 levels declined gradually from the immature stage to the post-spawning period, as in males.
In plain wordsIn female chub mackerel, the body's own kisspeptin gene activity in the brain fell from the immature stage to after spawning.
Peptide
Kisspeptin-10
Outcome
DecreaseKiss2 expression in brain of females across gonadal stages
Study
chub mackereln: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
However, Kiss2 levels fluctuated as that of males, gradually declining from the immature stage to the post-spawning period.
This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2069165207
08AnimalEndogenous levelAnimal study (in vivo)Other
In chub mackerel, pituitary Kiss1 levels did not fluctuate significantly across gonadal stages.
In plain wordsIn chub mackerel, the body's own kisspeptin gene activity in the pituitary gland did not change significantly across stages.
Peptide
Kisspeptin-10
Outcome
No significant changeKiss1 expression in pituitary across gonadal stages
Study
chub mackereln: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
The pituitary Kiss1 levels did not show significant fluctuations.
This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2069165208
09AnimalEndogenous levelAnimal study (in vivo)Other
In chub mackerel, gonadal Kiss1 levels were highly elevated during spermiation and late vitellogenesis compared with the immature and post-spawning periods.
In plain wordsIn chub mackerel, the body's own kisspeptin gene activity in the gonads was much higher during spermiation and late vitellogenesis than at other stages.
Peptide
Kisspeptin-10
Outcome
IncreaseKiss1 expression in gonads across gonadal stages
Study
chub mackereln: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
However, Kiss1 levels in the gonads were highly elevated during spermiation and late vitellogenesis compared to the immature and post-spawning period.
This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2069165209

Studies that did not test the peptide alone2

In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Kisspeptin-10.

10Computer modelNot a test of Kisspeptin-10 aloneIn silicoOther
Comparison of deduced amino acid sequences of chub mackerel Kiss1 and Kiss2 with other vertebrates showed high conservation only in the kisspeptin‑10 region.
In plain wordsA computer comparison of fish and other vertebrate sequences found high similarity only in the kisspeptin‑10 region.
Peptide
Kisspeptin-10
Outcome
Not applicableConservation of Kiss1 and Kiss2 amino acid sequences in the Kp-10 region
Study
chub mackereln: not reported in source
Outcome group
Receptor activity and mechanism · Pharmacology
Source sentences
Summary
A comparison of the deduced amino acid sequences of chub mackerel Kiss1 and Kiss2 with those of other vertebrate species showed a high degree of conservation only in the kisspeptin-10 region (Kp-10).
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-2069165210
11Computer modelNot a test of Kisspeptin-10 aloneIn silicoOther
The Kp-10 sequences of chub mackerel Kiss1 and Kiss2 differed at three amino acids.
In plain wordsA computer comparison found that the two chub mackerel Kp-10 sequences differ at three amino acids.
Peptide
Kisspeptin-10
Outcome
Not applicableAmino acid variation between chub mackerel Kiss1 and Kiss2 Kp-10
Study
chub mackereln: not reported in source
Outcome group
Receptor activity and mechanism · Pharmacology
Source sentences
Summary
The Kp-10 of chub mackerel Kiss1 (YNFNSFGLRY) and Kiss2 (FNFNPFGLRF) showed variations at three amino acids.
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-2069165211

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
10 Oct 2026, 09:43 UTC
Study results updated
Version 1
9 Oct 2026, 03:04 UTC
First added · source update from Europe PMC

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