Mapping of kisspeptin fibres in the brain of the pro-oestrous rat.

Desroziers E, Mikkelsen J, Simonneaux V, Keller M, Tillet Y, Caraty A, Franceschini I

Journal of neuroendocrinology1 Oct 2010Cited by 84 (Europe PMC)

PMID20673302DOI10.1111/j.1365-2826.2010.02053.xPepBankPUB-20673302

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01AnimalEndogenous levelAnimal study (in vivo)Other
In pro-oestrous rats, the body's own kisspeptin-immunoreactive cell bodies were found only in the arcuate nucleus, and fibres were confined to the septo-preoptico-hypothalamic continuum.
In plain wordsIn rats, the body's own kisspeptin was found in cell bodies only in one brain area, and in fibres in a defined region.
Peptide
Kisspeptin-10
Outcome
Not applicableLocation of kisspeptin cell bodies and fibres
Study
ratn: not reported in source
Outcome group
Sex hormones and fertility · Endocrine and hormones
Source sentences
Summary
With both antibodies, immunoreactive cell bodies were exclusively observed in the arcuate nucleus, and immunoreactive fibres were confined to the septo-preoptico-hypothalamic continuum of the brain.
1 context sentence(design, population, supporting numbers)
Summary · context
The present study aimed to investigate the distribution of kisspeptin neurone fibres in the female rat brain by comparing precisely the immunoreactive pattern obtained with two antibodies: one specifically directed against kisspeptin-52 (Kp-52), the longest isoform, and the other directed against ki…
This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2067330201
02AnimalEndogenous levelAnimal study (in vivo)Other
In pro-oestrous rats, the body's own kisspeptin fibres were found in the preoptic area, several hypothalamic nuclei and the median eminence.
In plain wordsIn rats, the body's own kisspeptin fibres were found in many brain regions, including the preoptic area and the median eminence.
Peptide
Kisspeptin-10
Outcome
Not applicableBrain regions containing kisspeptin fibres
Study
ratn: not reported in source
Outcome group
Sex hormones and fertility · Endocrine and hormones
Source sentences
Summary
Fibres were observed in the preoptic area, the diagonal band of Broca, the septohypothalamic area, the anteroventral periventricular, suprachiasmatic, supraoptic, paraventricular and periventricular nuclei, the dorsal border of the ventromedian nucleus, the dorsomedial and arcuate nuclei, and the median eminence.
1 context sentence(design, population, supporting numbers)
Summary · context
The present study aimed to investigate the distribution of kisspeptin neurone fibres in the female rat brain by comparing precisely the immunoreactive pattern obtained with two antibodies: one specifically directed against kisspeptin-52 (Kp-52), the longest isoform, and the other directed against ki…
This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2067330202

Studies that did not test the peptide alone2

In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Kisspeptin-10.

03AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Other
Most regions of immunoreactive cells and fibres matched for the anti-Kp-52 and anti-Kp-10 antibodies.
In plain wordsIn rat brain tissue, two antibodies gave matching staining in most regions.
Peptide
Kisspeptin-10
Outcome
Not applicableAgreement of anti-Kp-52 and anti-Kp-10 antibody staining
Study
ratn: not reported in source
Outcome group
Sex hormones and fertility · Endocrine and hormones
Source sentences
Summary
Most regions of immunoreactive cells and fibres matched perfectly for the two antibodies.
1 context sentence(design, population, supporting numbers)
Summary · context
The present study aimed to investigate the distribution of kisspeptin neurone fibres in the female rat brain by comparing precisely the immunoreactive pattern obtained with two antibodies: one specifically directed against kisspeptin-52 (Kp-52), the longest isoform, and the other directed against ki…
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-2067330203
04AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Other
Fibres in the dorsolateral septum, anterior fornix, accumbens nucleus and lateral bed nucleus of the stria terminalis were recognised only by the anti-Kp-10 antibody.
In plain wordsIn rat brain tissue, one antibody stained fibres in extra regions that the other antibody did not.
Peptide
Kisspeptin-10
Outcome
Not applicableAdditional fibres recognised only by anti-Kp-10 antibody
Study
ratn: not reported in source
Outcome group
Sex hormones and fertility · Endocrine and hormones
Source sentences
Summary
However, fibres in the dorsolateral septum, anterior fornix, accumbens nucleus and the lateral bed nucleus of the stria terminalis were only recognised by antibody anti-Kp-10
1 context sentence(design, population, supporting numbers)
Summary · context
The present study aimed to investigate the distribution of kisspeptin neurone fibres in the female rat brain by comparing precisely the immunoreactive pattern obtained with two antibodies: one specifically directed against kisspeptin-52 (Kp-52), the longest isoform, and the other directed against ki…
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-2067330204

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
10 Oct 2026, 09:43 UTC
Study results updated
Version 1
9 Oct 2026, 03:04 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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