Immunolocalization of humanin in human sperm and testis.

Moretti E, Giannerini V, Rossini L, Matsuoka M, Trabalzini L, Collodel G

Fertility and sterility9 Jun 2010Cited by 41 (Europe PMC)

PMID20542501DOI10.1016/j.fertnstert.2010.04.075PepBankPUB-20542501

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Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01HumanEndogenous levelObservational studyOther
Immunocytochemistry and immunoelectronmicroscopy showed that humanin is expressed in human ejaculated sperm and testis.
In plain wordsThe body's own humanin was found in human sperm and testis.
Peptide
Humanin
Outcome
Not applicableHumanin expression in human sperm and testis
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
We have discovered, by immunocytochemistry and immunoelectronmicroscopy, that humanin (HN) is expressed in human ejaculated sperm and testis.
This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2054250101
02HumanEndogenous levelObservational studyOther
Humanin localized mainly in the midpiece of sperm with normal morphology and in cytoplasmic residues and the entire tail of sperm with abnormal morphology.
In plain wordsThe body's own humanin sat in different parts of normal and abnormal sperm.
Peptide
Humanin
Outcome
Not applicableHumanin localization pattern by sperm morphology
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
In sperm, the HN immunolabeling pattern depends on sperm morphology; in particular, HN is mainly localized in the midpiece of sperm in semen samples with normal morphology and in cytoplasmic residues and entire tail in those with abnormal morphology.
This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2054250102
03HumanEndogenous levelObservational studyOther
Humanin was found in the cytoplasm and nucleus of spermatocytes and spermatids and in experimentally uncoiled chromatin of mature ejaculated sperm.
In plain wordsThe body's own humanin was found inside developing sperm cells and in the uncoiled DNA of mature sperm.
Peptide
Humanin
Outcome
Not applicableHumanin in germ cells and sperm chromatin
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
We also found HN in the cytoplasm and nucleus of spermatocytes and spermatids and in experimentally uncoiled chromatin of mature ejaculated sperm.
This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-2054250103

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
13 Oct 2026, 21:44 UTC
Study results updated
Version 1
13 Oct 2026, 16:31 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

Journal Article

MeSH terms

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